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Although early goal-directed therapy (EGDT) has been a landmark in guiding the approach to patients with sepsis in the ED, few institutions seem willing and able to adopt it for all eligible patients. 1 The complexity and invasiveness of the protocol are the most frequently cited barriers. In particular, it has been underlined that many clinicians would not feel comfortable with inserting a cen...

Much writing on party organisational development in post-communist East Central Europe has argued that, with the partial exception of successor parties to former regime parties, political parties in the region will be state-centred, low-membership organisations dominated by political elites, which loosely approximate to the ‘cartel’ and ‘electoral-professional’ models of party identified by som...

NATO’s enlargement into Central East Europe has been a lively debated topic for almost a decade. The highly variegated opinions and positions on this question in Europe and North America have ranged from angry denunciations, solid criticisms, serious doubts, guarded support to enthusiastic accolades. These contrasting attitudes underlined the flux and uncertainties as well as the divisibility o...

[The history of Australian company law has attracted remarkably little attention in academic literature, perhaps because it has mainly been seen as a copy of English law with few, if any, noteworthy features. This article points out several interesting and significant aspects of the evolution of Australian company law and considers this evolution in the context of the economic development of co...

Background/Aims: There are few studies in the literature that have evaluated the etiological factors in boys with central precocious puberty (CPP), and these studies are limited in terms of the sample size. In the present study, we aimed to evaluate the etiological factors in male CPP cases. Methods: One hundred male CPP subjects, aged between 9 months and 10.5 years, were included. The medical...

the disappearance of bipolar system following the disintegration of the soviet union, has also changed many strategic concepts. central asia, as a part of the soviet empire, has become an arena for regional and global challenges after these transformations. the region, already faced with various political, economic, social and cultural problems, soon became a location for the activities of isla...

• Objective: To evaluate the effectiveness of antimicrobialassociated central venous catheters (CVCs) and to estimate costs related to their use. • Method: Review of the literature. The clinical database from the University HealthSystem Consortium (UHC) was used to conduct a retrospective analysis of clinical and economic outcomes in adult patients who had a CVC placed while in the intensive ca...

The right to post the definitive version of the contribution as published at Cambridge Journals Online (in PDF or HTML form) in the Institutional Repository of the institution in which they worked at the time the paper was first submitted, or (for appropriate journals) in PubMed Central or UK PubMed Central, no sooner than one year after first publication of the paper in the journal, subject to...