this study aimed to evaluate the cellular toxicity of two newly-released acrylic resins (futura gen and gc reline hard) in comparison with the conventional heat-cure resin (meliodent).sample discs from each acrylic resin were placed in 24-well culture plates along with l929 mouse fibroblast cell line. a mixture of the rpmi 1640 medium, antibiotics and 10% fbs was added to the plates and the spe...

The toxic effects of digitalis are attributable in part to poisoning of the enzyme Na+-K+ ATPase and in part to the interactions of digitalis with the sympathetic and parasympathetic nervous systems. Additional modifiers of the toxic effects of digitalis include the concentrations of ions such as K+ and Ca2+, the age of the subject and the extent and type of cardiac disease. At the cellular ele...

objective(s):the neuroprotective effect offruit aqueous extract of ziziphus jujuba lam on glucose-induced neurotoxicity in pc12 cells as an appropriate in vitro model of diabetic neuropathy was investigated. materials and methods: cell viability was determined by the mtt assay. cellular reactive oxygen species (ros) generation was measured by dcfh-da analysis. cleaved caspase-3, a biochemical p...

edaravone, an antioxidant and radical scavenger, showed protective effects against oxidative stress-like condition. paraquat (pq) is a toxic herbicide considerable evidence suggests that oxidative stress and mitochondrial dysfunction contribute to pq toxicity. in this study, protective effect of edaravone against pq induced toxicity and reactive oxygen species (ros) generation in a549 cells and...

Objective(s): Early diagnosis of cancer using noninvasive imaging techniques has been discussed in several recent studies. The present study aimed to assess the synergistic effects of iodixanol-conjugated polyethylene glycol (PEG)-citrate (anionic linear globular) dendrimer G2 on MCF-7 breast cancer cells and human embryonic kidney 293 (HEK293) cells. Materials and Methods: PEG-citrate de...