Introduction: Spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. At present, the main source of data for cellular dosimetry is the s-values provided by MIRD. However, the MIRD s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. In this study, we used Geant4-DNA...

Motivated by an attempt to develop a method for solving initial value problems in a class of integrable cellular automata associated with crystal bases, we consider a generalization of a simple theorem in combinatorics. The original theorem asserts that any sequence of letters 1 and 2, and having no less 1’s than 2’s, can be changed into a ballot sequence via cyclic shifts only. Our theorem tre...

Paracetamol (acetaminophen, PCM) is a widely used over-the-counter analgesic and antipyretic drug. Intake of a large dose of PCM may result in severe hepatic necrosis. Oxidative stress is mediated by oxidative capacities of the PCM metabolite (N-acetyl-para-benzo quinoneimine, NAPQI), which covalently binds to proteins and other macromolecules to cause cellular damage. At low doses, NAPQI is ...

Cellular Automata (CA) represent an interesting approach to design Substitution Boxes (S-boxes) having good cryptographic properties and low implementation costs. From the cryptographic perspective, up to now there have been only ad-hoc studies about specific kinds of CA, the best known example being the χ nonlinear transformation used in Keccak. In this paper, we undertake a systematic investi...