micrornas (mirnas) represent a class of small non-coding rna molecules that regulate gene expression at the post-transcriptional level. they play a crucial role in diverse cellular pathways. ionizing radiation (ir) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. recently it has been discovered that mi...

exposure to high dosages of sulfur mustard (sm) can cause bone marrow depression, immune system suppression, impairment of the immune functions, and eventually results in diseases due to secondary immune disorders. in this article, we have studied the effects of this poison on iranian veterans by analysis of related published studies. in a systematic search, the effects of sm gas on iranian vic...

this study was conducted to compare the effects of different illumination programs on the cellular and humoral immune system using 320 one day–old male broilers (arian 386) in a completely randomized design of 8 replications (10 birds each). the four assayed lighting schedules were comprised of: 1- continuous lighting (control), 2- decrease then sudden increase of lighting, 3- decreasing-gradua...

background: naltrexone, an opioid receptor antagonist shifts the immune response toward a th1 profile. in the current study, we evaluated the efficacy of the mixture of ntx and alum, as a new adjuvant, to enhance immune response and induce protection against leishmania major in a mouse model. methods : balb/c mice were immunized three times either autoclaved l. major promastigotes’ antigens alo...

in this study, we investigate the immunostimulatory effects of alcoholic extract of the coffee seed on cell-mediated immune response andcyclophosphamide-induced (cp) immunosuppressed mice. the assessment of cellular immune function was carried out by the measurement of delayed-type hypersensitivity (dth) response. according to the literature survey, cyclophosphamide has only suppressing effect ...