Primitive hemopoietic progenitor cells from adult mouse marrow have been substantially enriched by virtue of a negative selection procedure with monoclonal antibodies. It has been possible to segregate erythroid progenitor cells at distinct stages of differentiation on the basis of their cell surface antigens. This has been achieved with two monoclonal antibodies reactive with the mature elemen...

Recently we demonstrated that the nonadherent (to plastic) fraction of human PBMC could be activated by IL-2 to inhibit Cryptococcus neoformans growth. Here we characterize the antifungal effector cells. Depletion by panning of natural killer (NK) (CD16+, CD56+) cells from nylon wool-treated, IL-2-activated PBMC markedly decreased lytic activity against a tumor cell target (K562) but did not af...

Background: CD90, a membrane-associated glycoprotein is a marker used to identify mesenchymal stem cells (MSCs). Recent studies have introduced CD90, which induces tumorigenic activity, as a cancer stem cell (CSC) marker in various malignancies. Blocking CD90 activity with anti-CD90 monoclonal antibodies enhanced anti-tumor effects. To date, highly specific antibody single-chain variable fragme...

Costimulatory signals provided by T cells are required for B cells to produce specific antibody to T-dependent antigen. We have investigated the suitability of using the CD40 culture system for the proliferation and differentiation of Ag-specific human B cells using cytomegalovirus (CMV) or tetanus toxoid (TT) as antigen. We modified the CD40 culture system (CD32-transfected L cells, anti-CD40,...

In this paper, we propose enhanced constant power panning (CPP) law which improves sound localization accuracy for two channel and multi-channel surround speaker layouts. Conventional CPP laws have different sound direction from panning angle, especially when the speakers are spread out widely. To overcome this drawback, we define a target angle and derive it by using directional psychoacoustic...

Distance-Based Amplitude Panning (DBAP) has recently been proposed as a new technique for panning sound sources in two and three dimensional spaces spaces. In this paper, DBAP is compared with two established alternatives, Ambisonics and Vector-Based Amplitude Panning, both objectively in terms of speaker gains and their variation with source position, and subjectively using listening tests to ...