To investigate the mechanism of azalomycin F5a against methicillin-resistant Staphylococcus aureus (MRSA), the conductivity of MRSA suspension and the adenylate kinase activity of MRSA culture were determined with the intervention of azalomycin F5a, which were significantly increased compared to those of blank controls. This inferred that azalomycin F5a could lead to the leakage of cellular sub...

There are evidences showing that adverse impacts of aluminum (Al) on plants growth and development are associated with its effect on plasma membrane and cell wall. Influence of Al on peroxidation of membrane lipids, wall-bound phenolics, lignin, soluble phenolics and the activity of certain enzymes involved in metabolism of phenols, i.e., phenylalanine ammonia lyase (PAL) and polyphenol oxidase...

Phospholipid bilayers are the basic structural element of biological membranes. They separate the various cell compartments found in eukaryotic cells and form the outer barrier (cell membrane or plasma membrane) of eukaryotic and prokaryotic cells separating the cytoplasm from the extra-cellular space. The composition of phospholipid bilayers varies with the cell type and function of the membra...

Phospholipid bilayer are the basic structural element of biological membranes. They separate the various cell compartments found in eukaryotic cells and form an outer barrier (cell membrane or plasma membrane) of eukaryotic and prokaryotic cells separating the cytoplasm from the extra-cellular space. The composition of phospholipid bilayers varies with the cell type and function of the membrane...

pythium irregulare oomycetes adapts with environmental changes including crude oil concentration by changing the composition of lipids in the cytoplasmic membrane and providing the required characteristics for adaptation in improper and stressful environmental situations. it was found that cultivation of pythium irregulare lx oomycetes in the nutrient media with different concentrations of crud...

Pythium irregulare oomycetes adapts with environmental changes including crude oil concentration by changing the composition of lipids in the cytoplasmic membrane and providing the required characteristics for adaptation in improper and stressful environmental situations. It was found that cultivation of Pythium irregulare LX oomycetes in the nutrient media with different concentrations of crud...

Human cell membranes consist of various lipids that are essential for their structure and function. It typically comprises phosphatidylcholine (POPC), phosphatidylethanolamine (POPE), phosphatidylserine (POPS), sphingomyelin (PSM), cholesterol (CHL). Several experimental computational techniques have been employed to characterize the composition human membranes, however, CHL enriched membrane i...

Supramolecular chemistry has garnered important interest in recent years toward improving therapeutic efficacy via drug delivery approaches. Although self-assemblies have been deeply investigated, the design of novel drugs leveraging supramolecular is less known. In this contribution, we show that a Low Molecular Weight Gel (LMWG) can elicit cancer cell apoptosis. This biological effect results...