The objective of the present work is to design sustained release matrix tablets of cefixime trihydrate by incorporating drug in a matrix made up of release retardant polymers, which prolong drug release leading to minimization of the peak and valley effect in the plasma and provide patient convenience. The effect of combination of polymers on parameters like release pattern, release mechanism o...

Floating matrix tablets of cefixime trihydrate were developed to prolong gastric residence time and to increase drug absorption and hence bioavailability. Hydrophilic polymers viz. HPMC K4M and Xanthan gum were incorporated in varied proportions to develop floating matrix tablets of cefixime by direct compression method. Buoyancy was achieved by adding an effervescent mixture of sodium bicarbon...

The present research involves effectual parameters on Cefixime trihydrate removal from aqueous solutions. Antibiotics are the main contributions in pharmaceutical waste; their presence causes major concern. The extensive utilization of antibiotics in aquaculture and prescriptions has led to the cultivation of various antibiotic-resistant bacteria and genes in wastewater. The UV-LED/S2O82- pr...