نتایج جستجو برای: ccp

تعداد نتایج: 2163  

2012
Marian L Burr Sebastien Viatte Marwan Bukhari Darren Plant Deborah P Symmons Wendy Thomson Anne Barton

INTRODUCTION The utility of reassessing anti-cyclic citrullinated peptide (anti-CCP) antibody status later in disease in patients presenting with early undifferentiated inflammatory polyarthritis, particularly in those who test negative for both anti-CCP and rheumatoid factor (RF) at baseline, remains unclear. We aimed therefore to determine the stability of CCP antibody status over time and th...

Journal: :The Israel Medical Association journal : IMAJ 2008
Anikó Kapitány Zoltán Szabó Gabriella Lakos Magdolna Aleksza Anikó Végvári Lilla Soós Zsolt Karányi Sándor Sipka Gyula Szegedi Zoltán Szekanecz

BACKGROUND The presence of anti-cyclic citrullinated peptide autoantibody is highly specific for rheumatoid arthritis. Certain HLA-DR4 (HLA-DRB1*04) alleles, also known as the "shared epitope," are associated with increased susceptibility to RA. In addition, these alleles may also have relevance for disease outcome. Anti-CCP antibody positivity has been associated with the presence of HLA-DR4 a...

2016
Lauren Lange Geoffrey M. Thiele Courtney McCracken Gabriel Wang Lori A. Ponder Sheila T. Angeles-Han Kelly A. Rouster-Stevens Aimee O. Hersh Larry B. Vogler John F. Bohnsack Shelly Abramowicz Ted R. Mikuls Sampath Prahalad

BACKGROUND The association between rheumatoid arthritis (RA) and periodontitis is well established. Some children with juvenile idiopathic arthritis (JIA) phenotypically resemble adults with RA, characterized by the presence of anti-cyclic citrullinated peptide (CCP) antibodies. We sought to investigate an association between CCP-positive JIA and symptoms of periodontitis and antibodies to oral...

Journal: :international journal of preventive medicine 0
rokhsareh meamar gholamreza askari majid ghasemi mohammad reza aghaye ghazvini sahar vesal mostafa sharifkhah

background: alzheimer’s disease (ad) is one of the most important neurodegenerative disorder. anti‑cyclic citrullinated peptide (anti‑ccp) may all be involved in the development of vascular disease such as ad. the aim of this study is detection of seropositivity for anti‑ccp antibody in ad patients. methods: in our study, 30 patients with ad and 29 healthy controls (age and‑sex matched) were re...

2011
Yun-Young Chang Surangi Dissanayake Jeong-Ho Yun Ui-Won Jung Chang-Sung Kim Kyeong-Jun Park Jung-Kiu Chai Seong-Ho Choi

PURPOSE The purpose of this study was to determine the biological effects of cyanoacrylate-combined calcium phosphate (CCP), in particular its potential to act as a physical barrier - functioning like a membrane - in rabbit calvarial defects. METHODS In each animal, four circular calvarial defects with a diameter of 8 mm were prepared and then filled with either nothing (control group) or one...

2015
Mónica Vázquez-Del Mercado Lourdes Nuñez-Atahualpa Mauricio Figueroa-Sánchez Eduardo Gómez-Bañuelos Alberto Daniel Rocha-Muñoz Beatriz Teresita Martín-Márquez Esther Guadalupe Corona-Sanchez Erika Aurora Martínez-García Héctor Macias-Reyes Laura Gonzalez-Lopez Jorge Ivan Gamez-Nava Rosa Elena Navarro-Hernandez María Alejandra Nuñez-Atahualpa Javier Andrade-Garduño

UNLABELLED The main cause of death in rheumatoid arthritis (RA) is cardiovascular events. We evaluated the relationship of anticyclic citrullinated peptide (anti-CCP) antibody levels with increased carotid intima-media thickness (cIMT) in RA patients. METHODS Forty-five anti-CCP positive and 37 anti-CCP negative RA patients, and 62 healthy controls (HC) were studied. All groups were assessed ...

2013
C Popescu S Zofotă V Bojincă R Ionescu

RATIONALE Anti-CCP antibodies are detectable not only in rheumatoid arthritis (RA), but also in psoriatic arthritis (PsA). It is possible those anti-CCP antibodies are associated with features of PsA and that these auto-antibodies are useful in distinguishing PsA from RA. OBJECTIVE to evaluate the prevalence and the associations of anti-CCP antibodies in PsA patients; to evaluate the usefulne...

Journal: :Reumatismo 2006
A Spadaro V Riccieri C Alessandri R Scrivo G Valesini

OBJECTIVE To assess the role of anti-cyclic citrullinated peptide (CCP) antibody detection in synovial fluid (SF) of RA patients compared to OA patients. METHODS We evaluated in 25 RA subjects and 14 OA patients, presenting a knee-joint effusion, the main clinical and laboratory parameters including the number of painful and/or swollen joints, Ritchie index, morning stiffness, ESR, CRP and an...

2015
Y. Saylan F. Yılmaz

In this study, we have focused our attention on combining of molecular imprinting into nanofilms and QCM nanosensor approaches and producing QCM nanosensor for antiCCP, chosen as model protein, using anti-CCP imprinted nanofilms. The nonimprinted nanosensor was also prepared to evaluate the selectivity of the imprinted nanosensor. Anti-CCP imprinted QCM nanosensor was tested for real time detec...

Journal: :Arthritis Research & Therapy 2005
Annette HM van der Helm-van Mil Kirsten N Verpoort Ferdinand C Breedveld René EM Toes Tom WJ Huizinga

Antibodies to citrullinated proteins (anti-cyclic-citrullinated peptide [anti-CCP] antibodies) are highly specific for rheumatoid arthritis (RA) and precede the onset of disease symptoms, indicating a pathogenetic role for these antibodies in RA. We recently showed that distinct genetic risk factors are associated with either anti-CCP-positive disease or anti-CCP-negative disease. These data ar...

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