Purpose: To develop a visual function-based deep learning system (DLS) using fundus images to screen for visually impaired cataracts. Materials and methods: A total of 8,395 (5,245 subjects) with corresponding function parameters collected from three clinical centers were used evaluate DLS classifying non-cataracts, mild cataracts, Three algorithms (DenseNet121, Inception V3, ResNet50) leverage...

purpose : cataract is one of the most common diseases of older ages and, at present, the leading cause of avoidable blindness in the world. along with the population growth, the rate of cataract surgeries is increasing in most countries worldwide. the number of cataract operations per million population per year is known as the cataract surgery rate (csr) and is one of the indicators introduced...

BACKGROUND Radiation cataracts develop as a consequence of the effects of ionizing radiation on the development of the lens of the eye with an opaque lens reducing or eliminating the ability to see. Therefore, we would expect cataracts to be associated with reduced fitness in free-living animals. METHODOLOGY/PRINCIPAL FINDINGS We investigated the incidence of lens opacities typical of catarac...

We identified a pedigree of Labrador retrievers (LR) that develop hereditary cataracts between 6 and 18 months of age. In humans, galactokinase deficiency is an autosomal recessive disorder characterized by juvenile onset of cataracts. 1 In order to evaluate GALK1 as a candidate gene, we cloned and sequenced the canine GALK1 gene and tested a single nucleotide polymorphism (SNP) in the gene for...

BACKGROUND Cataracts are one of the major public health problems worldwide. Ultraviolet radiation (UVR) is one of the risk factors for cataract development. We analyzed the relationship between disability-adjusted life year (DALY) rates of cataracts and UVR exposure in China. METHODS DALY rates of cataracts and UVR exposure in 31 regions of China were calculated based on data from the Second ...

BACKGROUND The antioxidant properties of tea extracts are considered to be effective in protecting against cataracts. However, there is still insufficient epidemiological knowledge about the protective effects of different types of tea on age-related cataracts. METHODS The data was derived from the Zhejiang Major Public Health Surveillance (ZJMPHS) Program on health and related factors in the...

the province of rudsar is located in the caspian littoral zone of iran. in 1970 an ophthalmic health survey was carried out in 25 units, which were selected by random sampling in these areas. a total of 2,165 persons were examined and the results of this evaluation have been prepared in 6 parts, consisting of ophthalmic conditions and health customs, infectious eye diseases, visual status and d...

PURPOSE To map a gene for cataracts in a family with congenital nuclear and sutural cataracts and to examine candidate genes in the linked region. METHODS A large family with autosomal dominant congenital nuclear and sutural cataracts was identified and characterized. A genome-wide screen was conducted with a set of markers spaced at 10- to 15-cM intervals, and linkage was assessed using stan...