1 Crossed Modules and Cat1-Groups 4 1.1 Pre-crossed and Crossed Modules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1.2 Examples of Crossed Modules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.3 Properties of Crossed Modules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.4 Sub-crossed modules . . . . . . . . . . . . . . . . . . . . . ....

Vegetative growth signaling of the opportunistic human pathogenic fungus Aspergillus fumigatus is mediated by GpaA (Gα). FlbA is a regulator of G protein signaling, which attenuates GpaA-mediated growth signaling in this fungus. The flbA deletion (ΔflbA) and the constitutively active GpaA (GpaA(Q204L)) mutants exhibit enhanced proliferation, precocious autolysis, and reduced asexual sporulation...

A simplicial group is a object in the category of groups. very nice application which polygroup given this paper. Using polygroups instead groups, we already had good results from well known properties due to Loday. Loday proved that crossed module, cat1-group, categories and whose Moore complex length one are equivalent. Loday’s idea present functor groups polygroups. We show there exist cat1-...

In the present study, we examined the role in hematopoiesis of cationic amino acid transporter 1 (CAT1), which transports L-arginine, L-lysine, L-ornithine, and L-histidine. The expression level of human CAT1 (hCAT1) mRNA in mononuclear cells (MNCs) fractionated according to lineage-selective markers was examined by reverse transcriptase-polymerase chain reaction. The expression of CAT1 in glyc...

Frustrated Lewis pairs (FLPs) has been applied to catalytic metal-free hydrogenation. Can the FLP reactivity be used for catalytic hydroamination? Using density functional theory (DFT) calculations, we have explored whether the molecules cat1-cat3, which were previously designed by integrating the dearomatization-aromatization effect and the FLP reactivity, can catalyze the intramolecular hydro...

In the present study, we identified factors of cognitive and physical performances predicting self-rated health perception (SRH) using an SRH questionnaire in 660 (298 men 362 women) upper-middle-aged community dwellers. addition, neuropsychological test battery ability tests were applied. A multiple regression analysis was conducted forced entry method; digit cancellation (D-CAT1), logical mem...

Cationic amino acid transport activity in a canine lens epithelial cells (LEC) line was investigated. The transporter activity of arginine was 0.424 ± 0.047 nmol/mg protein min, while the presence of N-ethylmaleimide, an inhibitor of the canine cationic amino acid transporter (CAT), reduced transport activity by 30%. A full-length cDNA sequence of canine CAT1 was 2558 bp long and was predicted ...

Survival of fungal species depends on the ability of these organisms to respond to environmental stresses. Osmotic stress or high levels of reactive oxygen species (ROS) can cause stress in fungi resulting in growth inhibition. Both eukaryotic and prokaryotic cells have developed numerous mechanisms to counteract and survive the stress in the presence of ROS. In many fungi, the HOG signaling pa...

Rickets and hyperparathyroidism caused by a defective vitamin D receptor (VDR) can be prevented in humans and animals by high calcium intake, suggesting that intestinal calcium absorption is critical for 1,25(OH)(2) vitamin D [1,25(OH)(2)D(3)] action on calcium homeostasis. We assessed the rate of serum (45)Ca accumulation within 10 min of oral gavage in two strains of VDR-knockout (KO) mice (L...

This study extends our previous work of using π-FLP strategy to develop metal-free hydrogenation catalysts. Using small MeN=CMe(2) imine (im1) as a model, we previously designed cat1 and cat2 catalysts. But it is unclear whether they are capable of catalyzing the hydrogenations of bulky imines. Using tBuN=C(H)Ph (im2) as a representative of large imines, we assessed the energetics of the cat1- ...