Nuclear factor κB (NF-κB) is a key factor in the development of chronic inflammation and is deeply involved in age-related and metabolic diseases development. These diseases have become a serious problem in cats. Sirtuin 1 (SIRT1) is associated with aging and metabolism through maintaining inflammation via NF-κB. In addition, fibroblasts are considered an important factor in the development of ...

Cats co-occupy one third of all residences in the United States. As common household pets, they serve as sources of joy and companionship for their owners. However, feline ownership also comes with its own inherent risks, as cats can transmit an array of diseases to their owners, ranging from trivial to fatal ailments. By understanding the pathogenesis of cat-associated diseases, owners and the...

BACKGROUND Mammalian sirtuins are homologs to the yeast silent information regulator 2 (Sir2), which is an NAD-dependent deacetylase. Sirtuins are comprised of 7 proteins, and each has different target proteins. Sirtuin 1 (SIRT1) plays important roles in maintaining metabolic functions and immune responses, and SIRT3 protects cells from oxidative stress-induced cell death. Both SIRT1 and SIRT3 ...

Free-roaming cat populations have been identified as a significant public health threat and are a source for several zoonotic diseases including rabies, toxoplasmosis, cutaneous larval migrans because of various nematode parasites, plague, tularemia and murine typhus. Several of these diseases are reported to cause mortality in humans and can cause other important health issues including aborti...

INTRODUCTION Inflammatory and infectious diseases of the cat's Nervous System (NS), despite the great progress made by veterinary neurology in the feline species over the last few decades, is still a relatively unknown field, which maintains various debated aspects. The aim of these notes is to address the updated, systematic and consequential approach to inflammatory / infectious neurological ...

The ability to express transgenes selectively within the lung will greatly facilitate the development of gene therapy for a variety of human diseases. We have demonstrated that aerosol administration of a chloramphenicol acetyltransferase (CAT) expression plasmid complexed to cationic liposomes produces high-level, lung-specific CAT gene expression in mice in vivo. Significant levels of CAT act...

Catalase (CAT) has a catalytic role in the decomposition of hydrogen peroxide (H2O2) and a peroxidic role in which the peroxide is utilized to oxidize a range of H donors. The objective of the present study was to determine whether alcohol consumption, medications, and diseases have an effect in the erythrocyte on CAT activity or not. For this purpose, the subjects were divided into three diffe...

At this time, many animal lovers keep pets. Cat or cattery owners sometimes find it difficult to diagnose pet cat diseases because are not the same as human diseases, which easy and provide visible symptoms. Horas Cattery is a breeding ground provider of adoption services, including Bengal cats. From observations authors at Cattery, understanding symptoms still lacking, so they rely on expertis...

Objective: Sarcomas are neoplasms of mesenchymal (stem cell) origin and are rare skin diseases of cats and may occur anywhere on the cat body.The main etiologies of soft tissue sarcomas are Feline sarcoma virus induced sarcomas, vaccine site sarcomas, trauma, inflammation and radiation. Methods: In March 2014, a three years old male domestic shorthair cat were referred to a private veterinary c...