OBJECTIVE Vitex agnus-castus (VAC) and its essential oil have been traditionally used to treat many conditions and symptoms such as premenstrual problems, mastalgia, inflammation, sexual dysfunction, and pain. In this study, the effects of essential oil extracted from Vitex agnus-castus (EOVAC) leaves were investigated in three behavioral models of nociception in adult male Wistar rats. MATER...

Vitex agnus-castus has a long tradition as a herbal remedy and was used in ancient times not only as an anaphrodisiac and for preserving chastity but also against diverse disturbances of the female genital system. In actual clinical trials, the fruit Agni casti fructus was shown to relieve premenstrual syndrome (PMS) and especially breast swelling and pain, due to its dopaminergic effect. Altho...

Aims: In this research, it was aimed to determine the phenolic components of Vitex agnus‐castus L. (Chaste) samples belonging Verbenaceae family, which is one significant medicinal plants our country.Methods and Results: agnus-castus leaf flower provided from during flowering grown under Karabörtlen area (81 m) ecological conditions. Samples were then dried in a semi-shadowy airy place at room ...

Resume of 'previous work.?Vaughan (1921) found that an aqueous infusion of the leaves of Vitex peduncularis, Wall, var. roxburghiana, was being used by the aboriginal tribe of Ranchi in malaria and blackwater fever. Though the medicinal properties of the members of the Vitex family (e.g. Vitex trifolia, negundo, etc.) have been elaborately described in the Ayurvedic system of medicine, the Vite...

Introduction: The gradual menopausal decline in oestrogens impairs function of the hypothalamic and limbic systems and, therefore, thermoregulation, vasomotor stability, mood regulation and psychological wellbeing. The significantly reduced dopaminergic activity and melatonin secretion increased in hot flushes, psychological symptoms and poor sleep quality. When hormone replacement therapy (HRT...

conclusions potent antifungal activity, make this plant an effective replacement treatment for fungal infections or fungal strains that are resistance to synthetic antifungals. results thirty-two components were identified in vitex agnus-castus eo. the main compound was alpha-pinene (19.48%). the total phenolic content of eo was determined as 82.26 ± 5.94 mg gallic acid equivalent (gae)/g eo. t...