Casein is the collective name for a family of milk proteins. In bovine milk, casein comprises four peptides: αS1, αS2, β, and κ, differing in their amino acid, phosphorus and carbohydrate content but similar in their amphiphilic character. Hydrophilic and hydrophobic regions of casein show block distribution in the protein chain. Casein peptides carry negative charge on their surface as a resul...

Casein-graft-dextran copolymer was produced using the Maillard reaction. The copolymer is molecularly soluble in neutral aqueous solution whereas beta-carotene is extremely insoluble. By the method of dialysis or evaporation then dispersing in water, the solubility of hydrophobic complex of casein and beta-carotene decreases whereas the solubility of dextran increases gradually, then nanopartic...

The poor water solubility and bioactivity of lipophilic phytochemicals can be potentially improved by delivery systems. In this study, a low-cost, low-energy, and organic solvent-free encapsulation technology was studied by utilizing the pH-dependent solubility properties of curcumin and self-assembly properties of sodium caseinate (NaCas). Curcumin was deprotonated and dissolved, while NaCas w...

We herein demonstrate a new sensing method for phosphopeptides by localized surface plasmon resonance (LSPR) using titania-coated gold nanoparticles immobilized on the surface of a glass slide as the sensing substrate and using UV-visible spectrophotometry as the detection tool. Titania has been known to be an effective substrate for binding with phosphorylated species. The detection principle ...

Sorafenib, a multikinase inhibitor used for the treatment of hepatocellular carcinoma, is limited by its low oral bioavailability. To overcome this drawback, we have developed novel camel milk casein-derived nanoparticles as drug delivery system. Camel casein not only biocompatible on administration but actually dietary protein pharmaceutical relevance. Casein because amphiphilic nature, self-a...

Unique physicochemical properties of nanoparticles make them a novel candidate in agriculture and related areas. In the present work, we have studied effect casein stabilized metal oxide nanoparticles, viz. AgNPs, AuNPs, CuONPs, on vitro propagation Scoparia dulcis L. We examined these callus induction, shoot regeneration, root regeneration capacity. It was observed that Ag, Au, CuO had interac...

Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...

Biocompatible hydroxyapatite nanocomposites are biocompatible, biodegradable and nontoxic have been paid many attentions as one of the most suitable vehicle for drug delivery use. Our objective in this work was to prepare and characterize caseins based HA nanocomposite in a colloidal form for drug delivery purposes. Casein biopolymer was firstly extracted from skimmed milk by adding acetic acid...

Enzymatic cross-linking by microbial transglutaminase is a prominent approach to modify the structure and techno-functional properties of food proteins such as casein. However, some factors that influence structure-function-interrelations are still unknown. In this study, size cross-linked sodium caseinate nanoparticles was modulated varying ionic milieu during incubation with enzyme. As reveal...

This work is aimed at preparation of small silver nanoparticles (Ag NPs) with various sizes using two-step preparation method. The silver bromide nanoparticles were prepared in the first step and they were reduced to metal silver nanoparticles in the second step. Size of prepared silver nanoparticles was controlled by using of several modifiers. Two surfactants (SDS and Tween 80) and two natura...