modeling of the connections per day with time series did not give good results (the errors in some case exceeded the 200%), one of the reason of this bad performance was represented by the sharp fluctuations of the number of connections. On the other hand the results obtained when modeling the average number of connections per week were encouraging. In particular, Figure 3 and Figure 4 report r...

Keeping a player within the flow in a game is a central goal for game designers, making the game neither too easy nor too hard. Dynamic Difficulty adjustment seeks to fulfill this goal by dynamically tuning difficulty according to player actions in the game. In this paper we demonstrate that case-based reasoning with time series can serve to automatically identify the ability of a player in a g...

The self-controlled case series method, commonly used to investigate potential associations between vaccines and adverse events, requires information on cases only and automatically controls all age-independent multiplicative confounders while allowing for an age-dependent baseline incidence. In the parametric version of the method, we modelled the age-specific relative incidence by using a pie...

This paper discusses the role and integration of knowledge discovery (KD) in case-based reasoning (CBR) systems. The general view is that KD is complementary to the task of knowledge retaining and it can be treated as a separate process outside the traditional CBR cycle. Unlike knowledge retaining that is mostly related to casespecific experience, KD aims at the elicitation of new knowledge tha...

conclusions congenital hyperinsulinism can have different inheritance pattern. autosomal recessive inheritance is more common but less frequently autosomal dominant inheritance can be seen. it appears that mutations in abcc8 gene can show both autosomal recessive and autosomal dominant inheritance of the disease. pcr followed by sanger sequencing proved to be an efficient method for mutation de...