spinal muscular atrophy (sma) is a common autosomal recessive neuromuscular disorder caused by the loss of α-motor neurons in the spinal cord. the survival motor neuron (smn) protein is encoded by 2 genes, smn1 and smn2. the most frequent mutation is the biallelic deletion of exon 7 of the smn1 gene. smn2 cannot compensate for the loss of smn1, due to the exclusion of exon 7. carrier frequency ...

In direct-conversion orthogonal frequency division multiplexing (OFDM) receivers, the impact of frequency-dependent I/Q mismatch (IQ-M) with carrier frequency offset (CFO) must be considered. A preamble-assisted estimation is developed to circumvent the frequencydependent IQ-M with CFO. The results of a simulation and an experiment show that the proposed method could provide good estimation eff...

A new method for frequency synchronization based upon Zero-Intermediate Frequency (Zero-IF) receiver and characteristics of the received signal’s power spectrum for MC-DSCDMA-Uplink system is proposed in this paper. In addition to this, employing Zero Correlation Zone (ZCZ) sequences, designed specifically for quasisynchronous uplink transmissions, is proposed to exploit frequency and temporal ...

Orthogonal frequency division multiplexing (OFDM) is an attractive technique to accomplish wired or wireless broadband communications. Since it has been adopted as the terrestrial digital-videobroadcasting standard in Europe, it has also subsequently been embedded into many broadband communication standards. Many techniques for frame timing and frequency synchronization of OFDM systems have bee...

In this paper, we propose a new frequency synchronization algorithm for orthogonal frequency division multiplexing (OFDM) systems requiring only one training symbol, based on a conventional method which requires two training symbols. While the timing synchronization is obtained by using the conventional method, the carrier frequency offset is efficiently estimated by the proposed method. It is ...

This paper presents a sensitivity analysis of filter bank multicarrier (FBMC) systems to carrier frequency offset (CFO) and timing offset. Although the emphasis of the paper is on the class of FBMC systems that are based on offset quadrature amplitude modulation (OQAM), the developed results are found applicable to cosine modulated-based FBMC systems as well. We assume that coarse CFO and timin...

Future military waveforms are most probably implemented on software defined radios capable to handle several waveforms. Implementation of several waveforms would require design of several receiver chains. In order to ease these design tasks, this paper describes a universal frequency domain baseband receiver structure. The structure may be used as a starting point to design receiver basebands f...

The description and performance analysis of a new OFDM/DQPSK signal receiver is considered in this paper. The proposed receiver has performance that is close to the performance for the coherent detection of the OFDM/DQPSK signal, in case of zero carrier frequency offset. In case of non-zero frequency offset, receiver with decision feedback differential detection (DFDD-OFDM) is often used in the...

spinal muscular atrophies (smas) are one of the more common autosomal recessive and single gene disorders. they are heterogeneous disorders, both in phenotypic and genotypic aspects. prevalence of these disorders are about 1 of every 6000 to 25000 live born babies in different ethnicities. in some chinese population prevalence of disease reported to be 1 in 50000. if it was true, carrier freque...