Present work was undergone to investigate antioxidant and anti inflammatory and wound healing effects of Litsea glutinosa in rats. The aqueous extract of Litsea glutinosa (250 and 500 mg/kg body weight) was studied for ant inflammatory in animal models. The activity was studied in some acute models Viz carragenan , histamine and dextrin induced rats paw edema against indomethacin as standard, a...

Aleurites moluccana (euphorbiaceae) has been extensively used in folk medicine for the treatment of ulcers, headache, fevers, diarrhea and hypocholesterolemia. Sterols, flavonoids and triterpenes have been isolated from the leaves of the plant. The methanolic extract of dried leaves of aleurites moluccana (AMME) was investigated for anti-inflammatory (carragenan induced rat paw oedema) and anti...

Here we have characterized perthamide C, a cyclopeptide from a Solomon Lithistid sponge Theonella swinhoei, which displays an anti-inflammatory/immunomodulatory activity. The study has been performed using the carragenan-induced mouse paw edema that displays an early (0-6 h) and a late phase (24-96 h). Perthamide C significantly inhibits neutrophils infiltration in tissue both in the early and ...

A series of novel Schiff’s bases of Indazolone derivatives were prepared by the reaction of ohydrozinobenzoic acid with con HCl and it gives 1,2-dihydro-indazol-3-one. The 3-indazolone is react with 4 substituted aniline, it produces various derivative of schiff’s bases of Indazolone. The Indazolone derivatives synthesized were Ia, Ib ,Ic, Id, Ie, If, Ig and Ih. The structures of the synthesize...

The main belief is that joints such as the knee and ankle joints are not innervated by nerves with a cholinergic function. That includes the assumption that these joints are not innervated by the vagus nerve (van Maanen et al., 2009a, see also Grimsholm et al., 2008). Accordingly, there is actually no morphologic proof of a cholinergic innervation of the knee joint, nor of the ankle joint. Desp...

This study was concerned with the investigation of acute pharmacological responses (pharmacodynamics) including analgesic and anti-inflammatory effects of ketorolac tromethamine fast dissolving tablets prepared by direct compression method using 3% croscarmellose sodium as a superdisintegrant by applying tail flick test and carragenan induced rat paw edema test respectively. Also, the work aime...

New mixed ligand complexes of Zn(II) with 1,10Phenanthroline and some amino acids were prepared in the solid form and characterized by elemental analysis, conductivity, magnetic moment measurement, FT-IR, 1 H-NMR, 13 C-NMR and FAB+ mass studies. To examine anti-inflammatory and analgesic activities of its complexes, some Swiss albino mice of 05-07 weeks old were taken. One dose of the test comp...

Nonsteroidal anti-inflammatory drugs often cause development of significant GI lesions. Selective inhibitors of prostaglandin G/H synthase/cyclooxygenase-2 (PGHS-2) enzyme and some dual inhibitors of PGHS/5-lipoxygenase (5-LO) enzymes have been reported to be potent anti-inflammatory compounds that carry a much lower risk of having GI irritating effects. We have evaluated the anti-inflammatory ...