BACKGROUND AND OBJECTIVES Carotid artery intima-media thickness (CIMT) has recently been recommended as a non-invasive tool for primary prevention of cardiovascular events; the association between CIMT and adverse cardiovascular events is well-known. We sought to evaluate the prevalence and significance of carotid artery plaque, especially in patients with coronary atherosclerosis. SUBJECTS A...

BACKGROUND The stroke is leading cause of death and severe disability worldwide. Atherosclerosis is responsible for over 30% of all ischemic strokes. It has been recently discovered that plaque morphology may help predict the clinical behavior of carotid atherosclerosis and determine the risk of stroke. The noninvasive imaging techniques have been developed to evaluate the vascular wall in an a...

BACKGROUND AND PURPOSE There is scant population-based evidence regarding extracranial carotid plaque surface irregularity and ischemic stroke. Using a prospective cohort design, we evaluated the association of carotid plaque surface irregularity and the risk of ischemic stroke in a multiethnic population. METHODS High-resolution B-mode ultrasound of the carotid arteries was performed in 1939...

BACKGROUND Type 2 diabetes mellitus (T2DM) might aggravate the carotid plaque vulnerability, and increase the risk for ischemic stroke. Few studies reported the acute stroke subtype with carotid plaque characteristics in T2DM patients. This study aimed to investigate the association between carotid plaque characteristics and acute cerebral infarct (ACI) lesion features determined by MRI in T2DM...

objective: atherosclerosis disease, inflammation and malnutrition have strong association with end stage renal disease (esrd). diabetes mellitus (dm) is the most commonly esrd causes. diabetic nephropathy (dn) could be associated with inflammation. type 2 diabetic patients with advanced nephropathy show the highest levels of inflammatory markers. this study was designed to determine the associa...

Carotid intima-media thickness (CIMT) has been shown to predict cardiovascular (CV) risk in multiple large studies. Careful evaluation of CIMT studies reveals discrepancies in the comprehensiveness with which CIMT is assessed-the number of carotid segments evaluated (common carotid artery [CCA], internal carotid artery [ICA], or the carotid bulb), the type of measurements made (mean or maximum ...

Introduction Identifying patients with carotid atherosclerosis at risk for ischemic stoke would greatly benefit patient outcomes. Recently, high-resolution methods have enabled MRI to noninvasively image the fine internal structure of the carotid plaque [1]. Some carotid plaque features, such as the presence of intraplaque hemorrhage (IPH) and thin or ruptured fibrous cap on multi-contrast weig...

BACKGROUND AND PURPOSE Increasing evidence suggests that carotid artery imaging can identify vulnerable plaque elements that increase stroke risk. We correlated recently proposed markers, soft and hard plaque thickness measurements on axial computed tomography angiography source images, with symptomatic disease status (ipsilateral stroke or transient ischemic attack) in high-grade carotid disea...

Carotid atherosclerotic plaques are a major cause of ischaemic stroke. The biomechanical environment to which the arterial wall and plaque is subjected to plays an important role in the initiation, progression and rupture of carotid plaques. MRI is frequently used to characterize the morphology of a carotid plaque, but new developments in MRI enable more functional assessment of carotid plaques...