BACKGROUND Shear stress gradients and inflammation have been causally associated with atherosclerosis development in carotid bifurcation regions. The mechanism underlying higher levels of carotid intima-media thickness observed among HIV-infected individuals remains unknown. METHODS AND RESULTS We measured carotid intima-media thickness progression and development of plaque in the common caro...

BACKGROUND The correlation of the common carotid artery (CCA) bifurcation and its surrounding structures is poorly described. The aim of this study was to describe the anatomy of the CCA bifurcation relative to its surrounding structures. METHOD We dissected a total of 67 carotid specimens from 36 embalmed cadavers. CCA bifurcation occurred at the superior border of thyroid cartilage in 39% a...

Carotid body tumors typically arise at the level of the common carotid bifurcation where the carotid body exists. Superior and inferior extension beyond the carotid body may occur as well, especially if the tumor is long-standing. We herein describe a case of carotid body tumor in a patient who presented with a right-sided neck mass for 30 years. Computed tomography angiography (CTA) and B-mode...

An aneurysm involved in common carotid artery (CCA) bifurcation is a rare clinical condition. There are not enough natural follow-up data, and there is no evidence-based treatment algorithm [1]. An endovascular approach is used to treat CCA bifurcation aneurysms, as it offers some advantages in selected patient populations; nonetheless, closure of the aneurysmal segment in CCA bifurcation using...

Numerous anatomic variants of the internal and external carotid arteries have been described [1-6]. We report on an unusual variant of external carotid artery anatomy in which no identifiable main external carotid trunk was present, and thus no true carotid bifurcation existed . The bifurcation as it existed was reduced to anomalous branching of a common facial-lingual trunk. Marked atheroscler...

Quantitative information about the geometry of the carotid artery bifurcation may help in predicting the development of atherosclerosis. A geodesic active contours based segmentation method combining both gradient and intensity information was developed for semi-automatic, accurate and robust quantification of the carotid bifurcation angle in Black Blood MRA data. The segmentation method was ev...

The purpose of this paper is to complement the characterization of patient-specific carotid artery bifurcation hemodynamics based on image data obtained by Doppler ultrasound imaging. A methodology for patient-specific 3D luminal surface reconstruction followed by structured hexahedral meshing of the volume and blood flow simulation is presented. Quantitative descriptors of the flow based on wa...

The numerical simulation has made tremendous advances in investigating the blood flow phenomenon through elastic arteries. Such study can be useful in demonstrating the disease progression and hemodynamics of cardiovascular diseases such as atherosclerosis. In the present study, patient specific case diagnosed with partially stenosed complete right ICA and normal left carotid bifurcation withou...

Eighty-eight percent of arteries in patients with amaurosis fugax or hemispheric transient ischemic attacks had angiographically demonstrable lesions at the carotid bifurcation. Eighty-one percent had stenoses or occlusions at the carotid bifurcation; 7 percent had ulcerative lesions without stenoses at this site. Forty-nine percent of arteries in these patients demonstrated ulcerative lesions ...

Quantitative information about the geometry of the carotid artery bifurcation is relevant for investigating the onset and progression of atherosclerotic disease. This paper proposes an automatic approach for quantifying the carotid bifurcation angle, carotid area ratio, carotid bulb size and the vessel tortuosity from multispectral MRI. First, the internal and external carotid centerlines are d...