background: candida albicans (c. albicans) may have cariogenic potential but its role in caries etiology has not been established. the aim of this study was to determine c. albicans in supragingival dental plaque and infected dentine of cervical and proximal in early childhood caries (ecc). methods: this cross-sectional study was carried out on 6o children aged 2-5 years, which were divided int...

OBJECTIVE To detect changes in the microbial richness of dental plaque and oral behaviors during caries development in young Chinese children. METHODS Supragingival plaque samples and a survey of oral behaviors of 130 children aged 3 at baseline were analyzed at 6 months and 12 months. Total DNA was isolated from all samples and PCR-denaturing gradient gel electrophoresis analysis was conduct...

Background: Alterations of oral microbiota are the main cause of the progression of caries. The goal of this study was to characterize the oral microbiota in childhood caries based on single-molecule real-time sequencing. Methods: A total of 21 preschoolers, aged 3-5 years old with severe early childhood caries, and 20 age-matched, caries-free children as controls were recruited. Saliva samples...

Dental caries (tooth decay) is an infectious disease. Its etiology is not fully understood from the microbiological perspective. This study characterizes the diversity of microbial flora in the saliva of children with and without dental caries. Children (3-4 years old) with caries (n = 20) and without caries (n = 20) were recruited. Unstimulated saliva (2 mL) was collected from each child and t...

background: early childhood caries (ecc) is one of the most common chronic child-hood diseases. in spite of the global decrease in dental caries in the past decades, ecc has become a significant problem in many developing countries and also in a few indus-trialized nations. saliva as a host factor can play an important role in the process of den-tal caries. objective: the aim of this study was ...

OBJECTIVE(S) The oral streptococci especially mutans Streptococci are related with the development of caries in humans. However, they are commonly distributed not only in populations with moderate or high caries incidence but also in populations having no or low caries experience. So, in this study, the differences between protein profiles of Streptococcus mutans from different sources were com...

PURPOSE This study was performed to compare the increment of carious surfaces per year in preschool-age children with early childhood caries (ECC), children with posterior caries only, and caries-free children after 7 to 10 years. METHODS One hundred and fifty files of children were included in the study. The first examination referred to the ages of 3 to 5 years (T1), and follow-up visits to...