M by the trend toward more collaboration in work flows, we study networks where some activities require the simultaneous processing by multiple types of multitasking human resources. Collaboration imposes constraints on the capacity of the process because multitasking resources have to be simultaneously at the right place. We introduce the notions of collaboration architecture and unavoidable b...

Capacity estimation is an important tool for the design and dimensioning of pedestrian facilities. The literature contains different procedures and specifications which show considerable differences with respect to the estimated flow values. Moreover do new experimental data indicate a stepwise growing of the capacity with the width and thus challenge the validity of the specific flow concept. ...

High-performance data centers have been aggressively moving toward parallel technologies like clustered computing and multi-core processors. While this increased use of parallelism overcomes the vast majority of computational bottlenecks, it shifts the performance bottlenecks to the storage I/O system. To ensure that compute clusters deliver the maximum performance, storage systems must be opti...

This paper deals with the service performance analysis and improvement using discrete event simulation has been used. The simulation of the health care has been done by arena master development 14-version software. The performance measurement for this study are patients output, service rate, service efficiency and it is directly related to waiting time of patients in each service station, work ...

In the face of growing competition software projects have to deliver software products faster and with better quality – thus leaving little room for unnecessary activities or non-optimal capacity. To achieve the desired high speed of the projects and the optimal capacity, bottlenecks existing in the projects have to be monitored and effectively removed. The objective of this research is to show...

C apacity utilization in U.S. industry features prominently in discussions of inflation. This prominence derives from the widely held viewpoint that “high” rates of capacity utilization are tantamount to resourceshortage conditions or “bottlenecks” that inevitably erupt into price inflation. For instance, an article in Citicorp’s Economic Week (January 18, 1994) argues: “In the past, a utilizat...

We study a stochastic network that consists of two servers shared by two classes of jobs. Class 1 jobs require a concurrent occupancy of both servers while class 2 jobs use one server only. The traffic intensity is such that both servers are bottlenecks, meaning the service capacity is equal to the offered workload. The real-time allocation of the service capacity among the job classes takes th...

Background In an effort to improve product yield of mammalian cell lines, we have previously demonstrated that our proprietary DNA elements, Selexis Genetic Elements (SGEs), increase the transcription of a given transgene, thus boosting the overall expression of a therapeutic protein drug in mammalian cells [1]. However, there are additional cellular bottlenecks, notably in the molecular machin...

The National Institute of Standards and Technology (NIST) high-speed quantum key distribution (QKD) system was designed to include custom hardware to support the generation and management of gigabit data streams. As our photonics improved our software sifting algorithm couldn’t keep up with the amount of data generated. To eliminate this problem we implemented the sifting algorithm into our pro...