نتایج جستجو برای: cancer drug
تعداد نتایج: 1431186 فیلتر نتایج به سال:
Cancer is one of the main causes of death worldwide. Chemotherapy is the most common method for cancer therapy which represent non-specific side effects on normal cells and tissues and drug resistance in cancer cells. There are two main mechanisms for Multi Drug Resistance (MDR) in cancer cells including: drug efflux pump and activation of anti-apoptotic pathways. Cancer chemotherapy disadvanta...
objective(s): many cancer cells show significant resistance to drugs that kill drug sensitive cancer cells and non-tumor cells and such resistance might be a consequence of the difference in metabolism. therefore, studying the metabolism of drug resistant cancer cells and comparison with drug sensitive and normal cell lines is the objective of this research. material and methods:metabolism of c...
objective(s):the colorectal cancer stem cells (cscs) with the cd133+ phenotype are a rare fraction of cancer cells with the ability of self-renewal, unlimited proliferation and resistance to treatment. quercetin has anticancer effects with the advantage of exhibiting low side effects. therefore, we evaluated the anticancer effects of quercetin and doxorubicin (dox) in ht29 cancer cells and its ...
in this thesis, we consider a mathematical model of cancer with completely unknown parameters. we study the stability of critical points which are biologically admissible. then we consider a control on the system and introduce situations at which solutions are attracted to critical points and so the cancer disease has auto healing. the lyapunov stability method is used for estimating the un...
Introduction: In recent years, the treatment strategy for infectious and autoimmune diseases has significantly changed. Up to now, cancer treatment has been conducted on the basis of clinical and pathological methods. The most common cancer treatments is limited to chemotherapy, radiation therapy and surgery. However, cancer treatment is still not optimal. Common challenges for treatment of cer...
nanoparticles have been at the center of research focus as a new promising material for the treatment of cancer in recent years. although many chemotherapy drugs for cancer treatment are available, their potential toxicity is the main point of concern. on the other hand, the conventional chemotherapeutic approach has not been found to be very efficient in colorectal cancer (crc) as the drug mol...
breast cancer is one of the most common malignancies among women. although chemotherapy remains a major therapeutic approach to treat cancers, drug therapy often fails for several reasons, particularly the drug resistance. resistance to multiple chemotherapeutic agents is one of the most important problems in the treatment of different types of cancers. therefore, in this study a resistant sub ...
بررسی تآثیر کورکومین بر بیان آکواپورین5 در سلول های سرطانی روده بزرگ انسان(ht-29) سرطان روده بزرگ جزو بیماری های خطرناک بوده و از نظر شیوع سومین سرطان شایع و دومین علت مرگ ومیر ناشی از سرطان در جهان محسوب می شود. خطرابتلا به این سرطان تحت تاثیر دو عامل محیطی وفاکتورهای ژنتیکی می باشد. آکواپورین ها، پروتئین های کانال آبی بوده که نقش مهمی را در انتقال آب در بافتهای اندوتلیالی و اپی تلیالی بر عهد...
cancer patients are more susceptible to adverse drug-drug interactions (ddis) due to receiving multiple medications especially chemotherapy medications, hormonal agents and supportive care drugs. the aim of this study is to describe the prevalence of potential ddis and to identify risk factors for these potential interactions in hospitalized cancer patients in a developing country.a cross-secti...
Abstract Drug delivery is one of the major issues in the world of science, which receives a large part of the research in various fields. The ultimate goal of drug delivery is to help the patient with developing advanced drug delivery systems. These systems revolutionize the treatment of many diseases including cancer. Effective drug carriers can significantly reduce the undesirable side effec...
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