Background & Aims: This study aimed to determine if serial measurement of serum CA-125 level could be used as a useful test in the differential diagnosis of intact and ruptured tubal pregnancies. Methods: In a single-blind prospective controlled clinical study, 59 women with tubal pregnancy of 6– 12 weeks (26 women with ruptured tubal pregnancy, 33 women with intact tubal pregnancy and 59women ...

The best available marker for epithelial ovarian cancer is still considered to be CA-125 due to a combination of reliability and general availability. HE4 is more sensitive than specific than CA-125, however the former is not in routine use. NICE still therefore recommends CA-125 rather than HE4. CA-125 is used for the diagnosis of epithelial ovarian cancer. αFP and βHCG are useful for identify...

larger tumor burden leads to higher serum ca-125 levels and the ability to perform optimal tumor cytoreduction of advanced ovarian cancer is also a function of tumor bulk. the purpose of this study was to identify the ability of preoperative serum ca-125 to predict possibility of optimal primary tumor cytoreduction in epithelial ovarian carcinoma (eoc). a total of 90 patients with eoc were eval...

By immunization of mice with the anti-CA 125 monoclonal antibody OC125, we tried to induce antibodies directed against the tumour-associated antigen CA125, via activation of the idiotypic network. Mice immunized by repeated administrations of F(ab')2-fragments of the OC125 antibody produced anti-idiotypic antibodies, imitating the original target antigen of the OC125. After induction of these a...