BACKGROUND AND AIMS Calotropis procera and Calotropis gigantea, originally from warm parts of Africa and Asia, are now pan-tropical and in ecological terms considered an indicator of overgrazed, disturbed lands; they grow successfully in dry areas. Variations in water relations, morphology and photosynthesis of the two species growing in the same habitat were studied to assess possible mechanis...

Macrolepiota procera, one of edible mushrooms belongs to Agaricaceae of Basidiomycota, has a good taste and good medicinal value. As a preliminary study for the development of artificial cultivation method of edible mushroom, cultural characteristics of M. procera was investigated on various culture media under different environmental conditions. Mycelial growth was compared on culture media co...

INTRODUCTION Calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. However, the precise mode of its pro-inflammatory effect is not known. In present study we have pharmacologically characterized the inflammation induced by latex of C. procera in a rat paw edema model and determined the role of histamine in late...

Received: Revised: Accepted: November 13, 2014 February 12, 2015 February 21, 2015 Gentamicin-induced nephrotoxicity is associated with free radicals generation in kidney tissue. Medicinal plants contain bioactive constituents that act as natural antioxidants, which can protect the biological system from oxidative stress. In this study, phytochemical constituents of aqueous extract of Calotropi...

Calotropis procera is a tropical medicinal plant known for its multiple curative effects on wide range of diseases. Current study has evaluated the antimitotic activity of the extracts of leaf and latex of C. procera on root meristem cells of Allium cepa. Onion bulbs were allowed to grow roots on moist cotton imbibed with solutions of test sample with known concentration of the extracts. Mitoti...

The side effects associated with the usage of synthetic antidiabetic drugs make it imperative to search for alternative drugs from medicinal plants. Therefore, this study was aimed at evaluating the α-amylase and α-glucosidase inhibitory potential of Calotropis procera leaf, as well as its possible mode of inhibiting these enzymes. Acetone, aqueous and ethanolic extracts of C. procera leaf was ...

Calotropis procera is traditionally used for treating many diseases including ulcers and tumors. It was thus deemed of interest to investigate and compare the antiulcer and cytotoxic activities of C. procera leaf, flower, and fruit extracts in an attempt to verify its traditional uses. Phytochemical studies on the fruits, flowers, and leaves of C. procera, collected from the desert of Saudi Ara...

procera produce milky white latex that causes inflammation of the skin and mucous membranes. Prostaglandins are one of the mediators released in an inflammatory response following induction of cyclooxygenase (COX). In the present study, we have evaluated the role of prostaglandins in inflammatory response elicited by the latex of C. procera . Methods: Aqueous extract of dried latex of C. procer...

OBJECTIVES The aim was to evaluate the effect of high molecular weight protein fraction of Calotropis procera latex on edema formation and oxidative stress in carrageenan-induced paw inflammation. METHODS A sub-plantar injection of carrageenan was given to induce edema in the hind paw of the rat. The inhibitory effect of high molecular weight protein fraction of C. procera latex was evaluated...

Phytochemical and biological screening is necessary for the isolation of new compound which lead to the discovery of drug. In the present work the crude MeOH extract and milky latex of Calotropis procera were tested for phytochemical test which indicated the presence of various class of bioactive secondary metabolite such as terpenoids, flavonoids, saponins, steroids and cardiac glycosides. C. ...