Background and Aims: Candida albicans (C. albicans) is the most common opportunistic human pathogen. Therapeutic options for Candida infections are limited to available antifungal drugs. The aim of this study was to investigate the effects of fluconazole/clotrimazole (FLU/CLT) on C. albicans hyphae formation. Materials and Methods: We have established the effectiveness of the combination of FL...

Objective(s) The fractions of Candida albicans have been used as an immunomodulator. The present work assessed the effect of different fractions of C. albicans on nitric oxide (NO) production by mice peritoneal macrophages. Materials and Methods Cell wall and cytoplasmic fractions of C. albicans ATCC 10321 strain were extracted. Mice peritoneal macrophages were purified and cultured. Differen...

Background: The leaves of Eucalyptus globulus (eucalyptus) are used for treatment of diabetes mellitus in traditional medicine. The aim of this study was to evaluate the effects of eucalyptus in treatment of established systemic infection with Candida albicans in normal and streptozotocin-induced diabetic rats. Methods: Sixty normoglycemic male Wistar rats, weighing 200-250 g, were selected and...

In this study, we evaluated the interactions between Candida albicans, Candida krusei and Candida glabrata in mixed infections. Initially, these interactions were studied in biofilms formed in vitro. CFU/mL values of C. albicans were lower in mixed biofilms when compared to the single biofilms, verifying 77% and 89% of C. albicans reduction when this species was associated with C. glabrata and ...

objective(s) the fractions of candida albicans have been used as an immunomodulator. the present work assessed the effect of different fractions of c. albicans on nitric oxide (no) production by mice peritoneal macrophages. materials and methods cell wall and cytoplasmic fractions of c. albicans atcc 10321 strain were extracted. mice peritoneal macrophages were purified and cultured. different ...

conclusions the results suggested that apr1 gene expression in c. albicans strains isolated from ms patients may be an important factor for invasive c. albicans strains in the progression of ms disease. results there was a statistically significant difference in apr1 gene expression of c. albicans strains between ms patients (mean ± sd: 0.5208 ± 0.11518) and the control group (mean ± sd: 0.7603...

Hasenclever, H. F. (U. S. Public Health Service, Bethesda, Md.), and William O. Mitchell. Antigenic studies of Candida. III. Comparative pathogenicity of Candida albicans group A, group B, and Candida stellatoidea. J. Bacteriol. 82:578-581. 1961.-Since the antigenic differences between Candida albicans group A and C. albicans group B had been established, the problem of a difference in pathogen...

Candida africana was previously proposed as a new species within the Candida albicans species complex, together with C. albicans and C. dubliniensis, although further phylogenetic analyses better support its status as an unusual variant within C. albicans. Here we show that C. africana can be distinguished from C. albicans and C. dubliniensis by pyrosequencing of a short region of ITS2, and we ...

background: due to the predisposing conditions in patients with cystic fibrosis (cf) caused by defective mucociliary clearance facilitating colonization and invasion with candida species has dramatically increased. traditional methods for identifying problems are imminent and time-consuming. therefore, molecular techniques utilizing amplification of target dna provide quick and precise methods ...