Burns commonly occur in children and their first aid remains inadequate despite burn prevention programmes. While scald injuries predominate, contact and flame burns remain common. Although typically less severe injuries overall than those in adults, hypertrophic scarring complicating both the burn wound and even donor sites occur more frequently in children. The heterogeneous nature of burn wo...

BACKGROUND Burn-induced inflammation leads to impaired immune responses resulting in increased morbidity and mortality. T-cells are central in the immune response and circulating CD4 and CD8 T-cells have been used to evaluate immune status; however, the role of these T-cell subsets in the burn wound is unknown. METHODS Male C57BL/6 mice were subjected to a major 3rd degree scald burn or sham ...

The response to major burn injury includes systemic release of mediators that may have an effect on wound healing. The authors evaluated the effect of a burn injury on the contraction of an excisional wound adjacent to the burn, and the effect of plasma derived from burn-injured animals on the contraction of the fibroblast-populated collagen matrix (FPCM). Nine rats (90-100 days old) under anes...

BACKGROUND The colonization of burn wounds by Pseudomonas aeruginosa can lead to septic shock, organ injuries, and high mortality rates. We hypothesized that negative pressure wound therapy (NPWT) would decrease invasion and proliferation of P. aeruginosa within the burn wound and reduce mortality. METHODS Thermal injuries were induced in anesthetized mice, and P. aeruginosa was applied to th...

objective(s): the aim of the present study was to evaluate the effect of quercus brantii galls extract on the rat skin burn wound healing. materials and methods: ethanol extract of the galls of q. brantii was used to treat the induced burn wounds on the back of 32 wistar rats divided into 4 groups. the groups were treated by placebo, 1%, 2% and 4% concentration gall extract gels for 14 days and...

aloe vera is a tropical plant belonging to the liliaceae family. it has beneficialeffects in variety of diseases. the aim of this study was to formulate a topical cream from a. vera with wound burn healing effect and to perform its clinical trial. a total of 30 patients (20 males and 10 females in the age range of 20-50 years) with second degree burn wounds on their both hands were selected for...

early wound excision and grafting of burn wounds is regarded not only as the method of choice in speeding up the healing process in deep burns, but also limits contracture and infection, on the other hand, smoking has generally been implicated in the delay of the healing process in a variety of surgical procedures, in this study we report the outcome of a cross-sectional study of all the 395 me...

The causative organisms of burn wound infection are aerobic and anaerobic bacteria, fungi, and yeasts [1,2]. Viral burn wound infection is rarely reported but does occur. Herpes virus family, including herpes simplex virus and varicella zoster virus, are the most frequent causative agents [3]. However, bacteria are the predominant isolates of burn wound infection. Aspergillus species are the mo...