Burkitt lymphoma is an aggressive lymphoma and its clinical, immunologic, chemical features are well-known. Burkitt lymphoma is in highgrade lymphomas and can spread very rapidly. Burkitt lymphoma has been difficult to be cured with conventional chemotherapy for adults. Early autologous bone marrow should be kept in mind in first remission BL. We presented a case of presenting with rapid and mu...

uterine lymphoma is a rare disease therefore, information regarding histologic type, immunophenotype of tumor cells and etiologic factors are limited. although secondary involvement of the genital tract occurs in up to 40% of cases• of disseminated lymphoma, lymphoma presenting with primary female genital tract . symptomatology is very unusual. we report a case of b-cell lymphoma in the uterine...

DH Burkitt lymphoma and Burkitt leukemia (also called mature B-cell acute lymphocytic leukemia [ALL]) have identical cytogenetic aberrations, surface markers, and molecular genetics. The clinical manifestations of Burkitt lymphoma resemble more of high grade malignant lymphomas, whereas B-cell ALL is similar to other subtypes of ALL. Additionally, there is a substantial difference in epidemiolo...

a 34-year-old hiv positive-man was admitted to the hospital due to fever and abdominal pain. constant and generalized abdominal pain started 3 months prior to admission (pta) in upper quadrants of abdomen followed by mild odynophagia, early satiety and more than 20 kg weight loss since then. intermittent fever begun 7 days pta and cough, sputum and dyspnea started since 5 days pta. his general ...

BACKGROUND Burkitt lymphoma is a high-grade B cell lymphoma which accounts for less than 1% of all adult cases of non-Hodgkin lymphoma. Rare instances of Burkitt lymphoma developing secondary to prior irradiation have been described in the literature. CASE PRESENTATION We report a case of a 90-year-old white woman with a recent history of irradiation for Hodgkin lymphoma, who presented with p...

Burkitt lymphoma is a cancer of the lymphatic system (in particular, B lymphocytes). It was named after Denis Parson Burkitt, a missionary doctor/surgeon and a research scientist, who first described the disease in 1958 while working in Equatorial Africa. In the original report, this type of lymphoma was described in the jaw of young African children. Dennis Burkitt was born in Ireland February...

Although Hedgehog signaling plays a major role in GLI1 transcription, there is now evidence suggesting that other pathways/genes, such as c-MYC, may also regulate GLI1 expression. We initiated studies in Burkitt lymphoma cells, which constitutively express c-MYC due to a chromosomal translocation, to determine whether Hedgehog or c-MYC regulates GLI1 expression. We show that all Burkitt lymphom...

Background: Burkitt lymphoma is a common subtype of non-Hodgkin lymphoma in children. It has a rapid and aggressive clinical course with frequent involvement of bone marrow and central nervous system. Systemic chemotherapy is the mainstay of the treatment for this malignancy in children. In this systematic review, we discuss autologous and allogeneic hematopoietic stem cell transplantation (HSC...

WITH the exception of leukamia, the vast majority of malignant tumours occurring in children consist of those developing in the central or autonomic nervous systems, the kidneys and the lymph glands (Campbell, Gainsford, Paterson and Steward, I96I). The metastases from these neoplasms are most frequently observed in the liver, the lungs and the skeleton, excluding the jaws. Among the rarest of ...