نتایج جستجو برای: buccal drug delivery
تعداد نتایج: 756418 فیلتر نتایج به سال:
Buccal patches are the types of formulations in which drug is administered through buccal mucosa. these or placed between gums and for pharmacological response. The main advantage there no first pass metabolism takes place easily absorb systemic circulation themucosa .the objective this delivery system to elevate increase bioavailability drug. review informs about steps involve preparation patc...
Among novel drug delivery systems, Buccal mucoadhesive systems have attracted great attention in recent years due to their ability to adhere and remain on the oral mucosa and to release their drug content gradually. Mucoadhesion may be defined as the process where polymers attach to biological substrate or a synthetic or natural macromolecule, to mucus or an epithelial surface. Buccal mucoadhes...
Bioadhesion can be defined as a phenomenon of interfacial molecular attractive forces in the midst of the surfaces of biological substrate and the natural or synthetic polymers, which allows the polymer to adhere to biological surface for an extended period of time. Within the oral mucosal cavity, the buccal region offers an adorable route of administration for systemic drug delivery. Among the...
mucoadhesive drug delivery systems were developed to sustain drug delivery via various mucus membranes for either local or systemic delivery of poorly absorbed drugs such as peptides and proteins as well as drugs that are subjected to high first-pass metabolism. the present study was undertaken to use isolated calendula mucilage as a mucoadhesive agent and to formulate controlled release buccoa...
Owing to the ease of the administration, the oral cavity is an attractive site for the delivery of drugs. Through this route it is possible to realize mucosal (local effect) and transmucosal (systemic effect) drug administration. In the first case, the aim is to achieve a site-specific release of the drug on the mucosa, whereas the second case involves drug absorption through the mucosal barrie...
The aim of this article is to study the buccal patches. Buccal patch is a nondissolving thin matrix modified release dosage form composed of one or more polymer films or layers containing the drug and/or other excipients. Buccal patches have been become an interesting area of novel drug delivery system as the dosage forms designed for buccal administration should not cause irritation and should...
The buccal mucosa is one of the administration sites that might provide an alternative for peroral administration. Mucoadhesive buccal drug delivery systems is one of the most important novel drug delivery systems with its various advantages and it has a lot of potential in formulating dosage forms for various chronic diseases. The delivery of drugs through the buccal mucosa has attracted much ...
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