Here, the first cDNA array analysis of differential gene expression in bovine spongiform encephalopathy (BSE) is reported, using a spotted cDNA array platform representing nearly 17 000 mouse genes. Array analysis identified 296 gene candidates for differential expression in brain tissue from VM mice in late-stage infection with the 301V strain of BSE, compared with brain tissue from normal, ag...

Aminosalicylates, corticosteroids and immunosuppressants are currently the therapeutic choices in inflammatory bowel diseases (IBD), however, with limited remission and often serious side effects. Meanwhile complementary and alternative medicine (CAM) use is increasing, particularly herbal medicine. Boswellia serrata is a traditional Ayurvedic remedy with anti-inflammatory properties, of intere...

Deep-inelastic structure functions are studied within a covariant scalar diquark spectator model of the nucleon. Treating the target as a two-body bound state of a quark and a scalar diquark, the Bethe-Salpeter equation (BSE) for the bound state vertex function is solved in the ladder approximation. The valence quark distribution is discussed in terms of the solutions of the BSE. PACS numbers: ...

Abstract In this paper, we propose a novel algorithm for blind source extraction (BSE) of moving acoustic recorded by multiple microphones. The is based on independent vector (IVE) where the contrast function optimized using auxiliary function-based technique and recently proposed constant separating (CSV) mixing model assumed. CSV allows movements extracted within analyzed batch recordings. We...

Statutory surveillance of bovine spongiform encephalopathy (BSE) indicates that cattle are susceptible to both classical BSE (C-BSE) and atypical forms of BSE. Atypical forms of BSE appear to be sporadic and thus may never be eradicated. A major challenge for prion surveillance is the lack of sufficiently practical and sensitive tests for routine BSE detection and strain discrimination. The rea...

In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.

OBJECTIVE The purpose of this study was to investigate the knowledge and practice of breast self-examination (BSE) among Saudi female nursing college students in Riyadh, Kingdom of Saudi Arabia (KSA). METHODS A cross-sectional study was conducted between October and December 2003. Saudi female nursing students (149) from the College of Applied Medical Sciences, King Saud University, and from ...

Nucleon structure functions, as measured in deep-inelastic lepton scattering, are studied within a covariant scalar diquark spectator model. Regarding the nucleon as an approximate two-body bound state of a quark and diquark, the Bethe-Salpeter equation (BSE) for the bound state vertex function is solved in the ladder approximation. The valence quark distribution is discussed in terms of the so...

The number of cases of Bovine Spongiform Encephalopathy (BSE) in the United Kingdom (UK) and Europe has decreased during the last years. The disease is designated as Classical BSE (C-BSE) once the prion protein involved is very constant and has genetic identity. On the other hand, atypical cases have occurred in several countries, apparently without any relationship with contaminated feeding. A...

Dendritic cells (DC) are suspected to be involved in transmissible spongiform encephalopathies, including bovine spongiform encephalopathy (BSE). We detected the disease-specific, protease-resistant prion protein (PrP(bse)) in splenic DC purified by magnetic cell sorting 45 days after intraperitoneal inoculation of BSE prions in immunocompetent mice. We showed that bone marrow-derived DC (BMDC)...