In asthmatic subjects there is a pronounced diurnal variation in bronchial responsiveness. If this phenomenon is due to variation in factors that control drug delivery, then it should be paralleled by a similar variation in competitive antagonist blockade. In order to study this possibility, we performed the methacholine challenge test and after 45 minutes, administered atropine by inhalat...

the purpose of this study was to determine the clinical significance of changes in the plasma  adiponectin  concentration  in  patients  with  bronchial  asthma  and  to  test  the association between the single nucleotide polymorphisms (snps) rs2241766 and rs1501299 in the adipoq gene and bronchial asthma in the chinese li population.we selected 120 cases and 120 controls, and plasma adiponect...

in asthmatic subjects there is a pronounced diurnal variation in bronchial responsiveness. if this phenomenon is due to variation in factors that control drug delivery, then it should be paralleled by a similar variation in competitive antagonist blockade. in order to study this possibility, we performed the methacholine challenge test and after 45 minutes, administered atropine by inhalation. ...

results: the lowest concentrations of nzvi that inhibited the visible growth (mic) of e. amylovora, x. oryzae, b. cereus and streptomyces spp. were 625, 550, 1250 and 1280 ppm, respectively. the minimum bactericidal concentration (mbc) for e. amylovora and x. oryzae were 10,000 and 5,000 ppm of nzvi, respectively. mbc was not observed for the gram positive bacteria. no bacteriostatic and bacter...

Sulfur mustard (SM) is a strong alkylating and mutagenic compound that targets humanairway system. We considered the expression of Forkhead box M1 (FOXM1) and apolipoproteinE (APOE) genes, which are responsible for cell proliferation, differentiation, tumorigenesis,and increased risk of lung cancer, in the lung bronchial tissue of patients exposed to SM.After performing pulmonary functional tes...

3-hydroxy-3-methylglutaryl-coa reductase inhibitors (statins), are effective serum cholesterol-lowering agents which also have anti-inflammatory properties. the objective of this study was to evaluate the effect of atorvastatin on bronchial hyperresponsiveness. adult patients (age 14 to 65 years) with bronchial hyperresponsiveness (bhr) diagnosis based on the spirometry with methacholine challe...

the purpose of the present study is to investigate the prevalence of th17 and regulatory t (treg) cells in children with allergic rhinitis (ar) accompanying with bronchial asthma (ba).24 children with ar, 22 children with ba, 18 children with ar accompanying with ba,and 20 healthy controls were recruited. the prevalence of peripheral blood th17 and treg cells were determined by flow cytometry. ...

Sulfur mustard (SM) is a strong alkylating and mutagenic compound that targets humanairway system. We considered the expression of Forkhead box M1 (FOXM1) and apolipoproteinE (APOE) genes, which are responsible for cell proliferation, differentiation, tumorigenesis,and increased risk of lung cancer, in the lung bronchial tissue of patients exposed to SM.After performing pulmonary functional tes...