OBJECTIVE To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta (E. hirta) in MCF-7 cell line model using comet assay. METHODS The cytotoxicity of E. hirta extract was investigated by employing brine shrimp lethality assay and the genotoxicity of E. hirta was assessed by using Comet assay. RESULTS Both toxicity tests exhibited significant toxicity result. In the comet as...

The organic extracts of leaves and roots of five plants used for treating malaria in Central, Nairobi and Rift Valley Provinces, Kenya were tested for brine shrimp lethality and in vitro antiplasmodial activity against chloroquine sensitive and resistant strains of Plasmodium falciparum. Of the plants tested, 60% were toxic to the brine shrimp (LC(50)<30 microg/ml) and eight out of ten plant pa...

Growth promoters play an important role in the animal agriculture industry as they facilitate to improve productivity mainly through reduction of pathogenic bacterial load in the gut. Ban and restrictions on the usage of Antibiotic Growth Promoters (AGP) due to public health concerns has made it essential to search alternatives from the herbal sources. But at the same time it is tricky to choos...

ABSTRACT: Candidiasis is a fungal infection caused by Candida albicans. Allium sativum (garlic) and Curcuma longa (turmeric) have been used as antifungal agents. The main aim of this study was to identify the effectiveness of these natural products towards C. albicans and on their pharmacological and toxicity aspects. Thus, agar disc diffusion method was used to study the antifungal activity of...

Euphorbiaceae is a family of plant spread in all parts of the world except very cold regions. The genus Euphorbia consists of over eighty-two species grown wildly in Iran. Some of Euphorbia species are used in the treatment cancer and tumors in different countries. The genus Euphorbia has been the source of a large number of biological active compounds. In this study petroleum ether, ether, eth...

Euphorbiaceae is a family of plant spread in all parts of the world except very cold regions. The genus Euphorbia consists of over eighty-two species grown wildly in Iran. Some of Euphorbia species are used in the treatment cancer and tumors in different countries. The genus Euphorbia has been the source of a large number of biological active compounds. In this study petroleum ether, ether, eth...

Currently, several desalination facilities have been proposed to operate or are actually operating in California. These facilities' use of reverse osmosis (RO) may discharge hypersaline reject brine into the marine environment. The risks, if any, this brine would pose to coastal receiving waters are unknown. To test the toxicity of hypersaline brine in the absence of any additional toxic consti...

General toxicity, antiproliferative, antibacterial and antioxidant activities of Caulerpa peltata J.V.Lamouroux (Caulerpaceae) collected from Oman Sea were investigated. Dried, ground alga was Soxhlet-extracted with hexane, dichloromethane and methanol successively. The methanol extract was subjected to vacuum liquid chromatography (VLC) fractionation on silica gel using a step gradient of diff...

Many plants are used for ethnoveterinary purposes in South Africa, particularly in rural areas. Extracts of 17 plant species employed to treat infectious diseases were prepared using three solvents and the antibacterial activity of the extracts was determined against two Gram-positive and two Gram-negative bacteria. Anthelmintic activity was evaluated against the free-living nematode Caenorhabd...