Cancer is one of the most distressing, life threatening disease regarding morbidity and mortality worldwide. Many folk medicinal and ornamental plants possess chemotherapeutic and chemo preventive potential. In present study, dichloromethane extract of wood, bark and root and methanol extracts of bark and root of Sanchezia speciosa were prepared. Sanchezia speciosa, an ornamental plant was eval...

Stationary liquid cultures of Fusarium tricinctum NRRL 3299 (synonym: F. sporotrichioides) produce T-2 toxin, neosolaniol, diacetoxyscirpenol, and HT-2 toxin when cultured on peptone-enriched Czapek Dox medium. At 15 and 27 degrees C, maximum T-2 toxin yield (265 and 50 mug/ml) was found after 10 to 14 and 7 days, respectively. The T-2 toxin in the culture medium was metabolized rapidly at 27 d...

Sesbania Grandiflora (Family: Leguminosae) is a medicinal plant used as tumor suppressant agent in Ayurveda, a traditional system of medicine practiced in sub-continental India. The aim of the study was to systematically investigate and reveal the cytotoxic potential of sesbania grandiflora bark extract [petroleum ether (BP), Chloroform (BC), Methanol extract (BM) and Aqueous extract (BA)] agai...

This study assessed the performance of a bioluminescent bacterial assay, the ToxScreen-II Test (Photobacterium leiognathi), in comparison to the brine shrimp (Artemia franciscana) nauplii lethality assay for the detection of toxicity associated with Aloe vera leaf gel extract and the organophosphate pesticide Mevinphos. In both bioassays, clear dose-response relationships were demonstrated for ...

Taylor et al. (1993) described a pollutant bioassay based upon a change in the rate at which Gammarus pulex (L.) consumes a novel food source (eggs of the brine shrimp Anemia salina) when the animals are stressed by exposure to a pollutant. The bioassay is rapid and non-destructive, and produces results with less variation than reported using conventional leaf-feeding bioassays. However, it is ...

In the present study, the crude methanolic extract of whole plant part of Blumea membranacea (Asteraceae) and its fractions obtained by Kupchan method were screened for their possible analgesic, cytotoxic and antioxidant activities. The analgesic activity of the samples was evaluated using acetic acid induced writhing method in Swiss-albino mice. In this method, acetic acid is administered intr...

The methanol extract of leaves of Urena lobata (L) (Malvaceae) has been selected to determine the antioxidant and cytotoxic potentials. The crude extract were tested for in vitro free radical scavenging assays such as 1, 1 diphenyl-2-picryl-hydrazyl (DPPH). Total phenolic and flavonoids content of U. lobata were analyzed. The sample effectively scavenged free radical at all different concentrat...

The present study was intended to determine the antioxidant, larvicidal, and cytotoxic potential of various extracts of Asplenium aethiopicum (Burm. f.) Becherer. Antioxidant potential of the extracts was determined by the DPPH radical scavenging, phosphomolybdenum, and scavenging of H2O2. Larvicidal activity of Asplenium aethiopicum was performed against the fourth instar larvae Culex quinquef...

Bioassay-guided fractionation was performed on a crude dichloromethane extract of Kaempferia galanga L. using chromatography techniques. Screening of the extract for biological activity started with the brine shrimp lethality bioassay, followed by the study of its antihypertensive activity on anaesthetized rats, which involved monitoring of the extract's effect on mean arterial blood pressure. ...