Introduction: Long-term teletherapy program is not suitable for old and working patients and those living in areas where little access to primary health care is available. Accelerated partial breast irradiation (APBI) using high dose rate (HDR) brachytherapy is an appropriate alternative for these patients due to its limited number of fractions. The AccuBoost is a system for delivering APBI. Th...

Introduction: Accuboost is a HDR brachytherapy system in early stages breast cancer treatment. This device provides a completely noninvasive procedure with parallel-opposed radiation from two immobilizing peripheral applicators that caused it a preferred option of modalities to choose. In most commercial treatment planning systems, tissues are considered as a simple water phan...

PURPOSE We present a novel algorithm for computer simulation of breast anatomy for generation of anthropomorphic software breast phantoms. A realistic breast simulation is necessary for preclinical validation of volumetric imaging modalities. METHODS The anthropomorphic software breast phantom simulates the skin, regions of adipose and fibroglandular tissue, and the matrix of Cooper's ligamen...

OBJECTIVE To evaluate our initial experience with a cone-beam breast computed tomography (BCT)-guided breast biopsy system for lesion retrieval in phantom studies for use with a cone-beam BCT imaging system. MATERIALS AND METHODS Under the Institutional Review Board approval, a phantom biopsy study was performed using a dedicated BCT-guided biopsy system. Fifteen biopsies were performed on ea...

With the increased incidence of cancer and a similarly increased number of surgeries for insertion of silicone breast implants, it is necessary to assess the effect of such material within the breast tissue, particularly in mammography, because of the reduction in the power of breast cancer diagnosis. In this work, we introduce a breast phantom with silicone implants in order to evaluate the in...

A feasibility study of an electrical impedance mammography (EIM) system with a rotary planar electrode array, named RPEIM, is presented. The RPEIM system is an evolution of the Sussex MK4 system, which is a prototype instrument for breast cancer detection. Comparing it with the other planar electrode EIM systems, the rotation feature enables a dramatic increase in the number of independent meas...

Software anthropomorphic breast phantoms have been used in virtual clinical trials for preclinical validation of breast imaging systems. Virtual trial quality depends largely on the realism of the simulated breast anatomy. Our phantom design has been focused on the simulation of large-scale and mesoscale anatomical structures, including the breast outline, skin, and matrix of Cooper’s ligaments...

Digital Breast Tomosynthesis (DBT) is a technology that creates three dimensional (3D) images of breast tissue. Tomosynthesis mammography detects lesions that are not detectable with other imaging systems. If image reconstruction time is in the order of seconds, we can use Tomosynthesis systems to perform Tomosynthesis-guided Interventional procedures. This research has been designed to study u...

Microcalcification is one of the earliest and main indicators of breast cancer. Because dual-energy digital mammography could suppress the contrast between the adipose and glandular tissues of the breast, it is considered a promising technique that will improve the detection of microcalcification. In dual-energy digital mammography, the imaged object is a human breast, while in calibration meas...