This paper reports a descriptive study of the costs and quality of life (QoL) outcome of treatments for early stage breast cancer in a cohort of Australian women, one year after initial surgical treatment. Mastectomy without breast reconstruction is compared to breast conserving surgery and radiotherapy (breast conservation). Of the 397 women eligible for the study, costing data were collected ...

BACKGROUND Positive margins after breast conservation surgery occur frequently and negatively influence local control rates. HYPOTHESIS Preoperative breast ultrasonography reduces the incidence of positive margins during breast conservation surgery. DESIGN Case-control analysis. PATIENTS AND INTERVENTION One hundred twenty-two consecutive patients with invasive breast cancer were studied....

background: breast conservation therapy (bct) is the standard of care for early stage breast cancer. the procedure can be a challenge for the surgeon if the lesion is non-palpable. for excision of non-palpable breast lesions, they should be localized precisely before surgery. there are different techniques such as the wgl (wire guided localization), roll (radio-guided occult lesion localization...

OBJECTIVE It has been proposed that young women should not be treated by breast conservation treatment because of a higher risk of local recurrences and worse survival. We therefore examined whether breast conservation treatment in young Chinese women yielded inferior clinical outcomes compared to modified radical mastectomy. DESIGN Retrospective study. SETTING Clinical oncology department ...

BACKGROUND Breast-conservation surgery with radiotherapy is a treatment highly recommended by the guidelines from the National Comprehensive Cancer Network. However, several variables influence the final receipt of radiotherapy and it might not be administered to breast cancer patients. Our objective is to propose a systematic framework to identify the clinical and non-clinical variables that i...

This issue includes information from the innovative research ongoing in breast cancer to increase our efficacy and therapeutic choices to adequately treat breast cancers with breast conservation. First a couple of articles address the biologic issues that form the basis of current therapies and how these may be improved with new biologic understandings. We are beginning to recognize that the br...

HYPOTHESIS Resection of the nipple-areolar complex (NAC) for central breast cancers that involve the nipple or areola, with postoperative radiation therapy, adheres to the oncologic principles established for breast conservation surgery of other breast cancers. Good or excellent cosmetic results can be achieved. The rate of ipsilateral breast recurrence will be similar to that seen with periphe...