Objective: Gut–brain axis (GBA) is very important in creation and modulation of gastrointestinal problems. Aloe vera gel has gastroprotective properties. The purpose of this study was to evaluate the effect of aqueous extract of Aloe vera leaves on the gastric acid secretion and brain and intestinal water content following acetic acid gastric ulcer induction. Materials and Methods: Gastric ulce...

This study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (CPB) and to explore the underlying mechanism. Twenty-four male adult Sprague Dawley (SD) rats were divided into 4 groups. Then, the rat CPB model was established. A 14G trocar was inserted into the atrium dextrum. For rats in S1 and S5 groups, sufentanil (1 µg•kg-1...

This study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (CPB) and to explore the underlying mechanism. Twenty-four male adult Sprague Dawley (SD) rats were divided into 4 groups. Then, the rat CPB model was established. A 14G trocar was inserted into the atrium dextrum. For rats in S1 and S5 groups, sufentanil (1 µg•kg-1...

this study aimed to observe the protective effects of sufentanil pretreatment on rat cerebral injury during cardiopulmonary bypass (cpb) and to explore the underlying mechanism. twenty-four male adult sprague dawley (sd) rats were divided into 4 groups. then, the rat cpb model was established. a 14g trocar was inserted into the atrium dextrum. for rats in s1 and s5 groups, sufentanil (1 µg•kg-1...

Quantitative mapping of water content, especially in the human brain, has the potential to provide important information for the study and diagnosis of diseases associated with a focal or global change in tissue water homeostasis. In the current work, an imaging method for the precise and accurate quantification of tissue water content is presented. The method allows the acquisition of water co...

Sysyn, Gregory D., Katherine H. Petersson, Clifford S. Patlak, Grazyna B. Sadowska, and Barbara S. Stonestreet. Effects of postnatal dexamethasone on bloodbrain barrier permeability and brain water content in newborn lambs. Am J Physiol Regulatory Integrative Comp Physiol 280: R547–R553, 2001.—We showed that antenatal corticosteroids reduced blood-brain barrier permeability in fetuses at 60 and...

Sysyn, Gregory D., Katherine H. Petersson, Clifford S. Patlak, Grazyna B. Sadowska, and Barbara S. Stonestreet. Effects of postnatal dexamethasone on bloodbrain barrier permeability and brain water content in newborn lambs. Am J Physiol Regulatory Integrative Comp Physiol 280: R547–R553, 2001.—We showed that antenatal corticosteroids reduced blood-brain barrier permeability in fetuses at 60 and...

Objective(s):Estrogen (E2) has neuroprotective effects on blood-brain-barrier (BBB) after traumatic brain injury (TBI). In order to investigate the roles of estrogen receptors (ERs) in these effects, ER-α antagonist (MPP) and, ER-β antagonist (PHTPP), or non-selective estrogen receptors antagonist (ICI 182780) were administered. Materials and Methods: Ovariectomized rats were divided into 10 gr...