Background: The aging process is associated with a progressive deterioration of tissues and organs. Apoptotic cell death has been known as a possible causal factor in age-related pathologies. Therefore, this study was conducted to assess the effect of regular high-intensity interval exercise on some apoptotic factors in the brain tissue of aged female rats. Materials and Methods: In this exper...

Aging, which is a natural process in an organism’s functions decline, present all living organisms. As we age, our brains begin to break down—certain brain regions get smaller and certain cell types decrease number. These changes are similar those seen diseases like Alzheimer’s Parkinson’s diseases. The similarities between aging these neurodegenerative tells us that the same genes might be aff...

neuronal and astroglial cells were prepared from whole brain of three month and 30-month- old rats for study of alterations in the nuclear poly adp-ribosylation and dna breaks with age. the relative purity of the cell preparations was confirmed by the determination of the neurofilament (low molecular weight) and glutamine synthetase content of the cells using elisa. an increase (75%) in the pol...