conclusions our study shows a relationship between cimt and renal parameters, including egfr and albuminuria. this study confirms the importance of intensive examinations for early detection of atherosclerosis and treatment of risk factors. patients and methods this cross-sectional study was included 205 patients with type 2 diabetes mellitus (t2dm). we recorded clinical and biochemical data su...

OBJECTIVE There is some evidence that people who score higher on tests of intelligence in childhood have lower carotid intima-media thickness and higher ankle brachial index in middle age. These findings need replicating in other, older populations. We investigated the prospective relationship between intelligence in childhood and atherosclerosis in the carotid and peripheral arteries at age 73...

BACKGROUND There is a need to identify sensitive biomarkers of early tobacco-related cardiovascular disease. We examined the association of smoking status, burden, time since quitting, and intensity, with markers of inflammation and subclinical atherosclerosis. METHODS AND RESULTS We studied 14 103 participants without clinical cardiovascular disease in ELSA-Brasil (Brazilian Longitudinal Stu...

To determine whether carotid intima media thickness is increased in children with primary hypertension, the current study compared carotid intima media thickness in hypertensive children with that of normotensive control subjects matched closely for body mass index and determined the relationship between carotid intima media thickness and hypertension severity determined by ambulatory blood pre...

Endothelial dysfunction has been reported to be the initial step in atherosclerosis. A noninvasive technique that uses ultrasound to measure the intima-media thickness of the carotid artery has been applied to evaluate localized atherosclerosis. This study was undertaken to elucidate whether endothelial dysfunction in the brachial artery is related to the intima-media thickness of the carotid a...

BACKGROUND Type 2 diabetes is strongly linked to an increased incidence of cardiovascular outcomes. Carotid artery intima-media thickness and ankle-arm index are non-invasive complementary measures as subclinical markers of atherosclerosis. OBJECTIVE To evaluate the association of carotid intima-media thickness, ankle-arm index, and inflammation profile in Mexican patients with early- and lat...

BACKGROUND The present study analyses the relation between smoking status and the parameters used to assess vascular structure and function. METHODS This cross-sectional, multi-centre study involved a random sample of 1553 participants from the EVIDENT study. MEASUREMENTS The smoking status, peripheral augmentation index and ankle-brachial index were measured in all participants. In a small...

BACKGROUND Subjects with type 2 diabetes are at an increased risk of vascular complications. The use of carotid ultrasound remains an attractive, non-invasive method to monitor atherosclerotic disease progression and/or response to treatment in patients with type 2 diabetes, with intima-media thickness routinely used as the gold standard to detect pathology. However, alternative measurements, s...

Objective: To examine the association of common carotid intima media thickness (CCA-IMT) with risk factors of atherosclerosis in type 2 diabetes and hypertension patients. Methods: This cross-sectional descriptive study was carried out in 14 type 2 diabetes, 15 hypertension and 15 control subjects. CCA-IMT and ankle brachial index (ABI) were measured by ultrasonography. Anthropometric character...

BACKGROUND We examined the relationship between central blood pressure (BP), brachial BP with carotid atherosclerosis and microvascular complications in type 2 diabetes mellitus (T2DM). METHODS We recruited 201 patients who were evaluated for central BP, brachial BP, carotid ultrasonography, brachial-ankle pulse wave velocity (baPWV), ankle-brachial index (ABI) and microvascular complications...