Response surface methodology was engaged for the optimization of diverse nutritional and physical parameters for laccase production by Streptomyces chartreusis strain NBRC 12753 in the submerged fermentation process. Screening of production parameters was executed using Plackett–Burman design and the variables with statistically momentous effects on laccase production were recognized. Variables...

Box-Behnken designs (Box and Behnken, 1958, 1960) form a very popular class of 3-level second-order designs when the number of factors is small, typically, seven or less. For larger number of factors these designs are not so popular because then, these designs require a large number of runs. This paper provides a catalog of 3-level second-order designs for 5-11 factors with run sizes ≤ 100. All...

a soil bacterium capable of degrading chitin on chitin agar plates was isolated and identified as bacillus pumilus isolate u5 on the basis of 16s rdna sequence analysis. in order to optimize culture conditions for chitinase production by this bacterium, a two step approach was employed. first, the effects of several medium components were studied using the plackett-burman design. among various ...

Degradation of Nitrobenzene in an Aqueous Environment through Fenton-like Process Using Box–Behnken Design Method

the current investigation presents the role of gooseberry (phyllanthus acidus) seeds as an effective biosorbent for remediating chromium (vi)), a toxic heavy metal pollutant commonly found in effluents from tanneries and relevant industries. biosorption was affected by ph, temperature and initial metal concentration. furthermore, there is a need to understand the holistic effect of all variable...

Purpose: To study the effect of some factors on the size of finasteride nano-emulsion by chemometric approach which could predict the size of nano-emulsion droplets under different conditions. Methods: Nano-emulsions were prepared using spontaneous emulsification method which occurs when organic and aqueous phases are mixed. The organic phase was a homogeneous solution of oil (finasteride as a ...

A statistical programme using Box-Behnken design, which applies a response optimization algorithm, was used to calculate and optimize simultaneously the lactic acid extraction by emulsion liquid membrane (ELM) in a mixed flow reactor. A 3-level Box-Behnken design with seven variables i.e. lactic acid concentration, internal reagent concentration, Alamine 336 fraction in oleyl alcohol, stirring ...