©2017 Blue Cross and Blue Shield of Louisiana An independent licensee of the Blue Cross and Blue Shield Association No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, or otherwise, without permission from Blue Cross and Blue Shield of Louisiana. Page 1 of 36 Applies to all products admin...

©2014 Blue Cross and Blue Shield of Louisiana An independent licensee of the Blue Cross and Blue Shield Association No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, or otherwise, without permission from Blue Cross and Blue Shield of Louisiana. Page 1 of 30 Applies to all products admin...

since its first description of botulism toxicity in 1820s, specific formulations of botulinum neurotoxin (bont) have been introduced with different clinical benefits. however, there is increasing number of adverse events reported to food and drug administration. this report presents the case of 62-year-old woman with parkinson’s disease who received bont injections to treat painful spasticity i...

a 39-year-old iranian female patient who was a known case of primary cervical dystonia since 10 years ago presented to a private office for dysport injection. the patients experienced severe dysphagia after inferior alveolar nerve block which was preceded by cervical botolinum toxin injection. a possible synergistic effect of botolinum toxin and lidocaine to produce severe dysphagia is presente...

Clostridium botulinum type A does not produce a 12,000 molecular weight toxin. The reported isolation of such a material by Gerwing et al. could not be confirmed.

The cosmetic uses of botulinum toxin (BoNT) are the most commonly used of its applications. Interest started after the effect of BoNT was shown in the treatment of blepharospasm and the first description of botulinum toxin for treatment of glabellar frown lines was in 1992. At that time, the use of this potent neurotoxin for cosmetic indications was an interesting footnote to treatments for str...

The most poisonous substance known to man, botulinum toxin has successfully established itself as a therapeutic agent over the years. Initially used to treat strabismus, botulinum toxin is now an accepted treatment in a wide spectrum of disorders and has over a 100 potential medical applications. The somewhat loosely-applied term 'wonder drug' could not be better employed to describe the remedi...