Dedication To my parents, family, and Ashley for their undying support and encouragement. v Acknowledgements There are many friends and co-workers who contributed to the completion of this work. I would like to thank the Gottlieb laboratory members and neighboring labs for their advice and reagents. I am very grateful to Dr. Bose (and laboratory), who was gracious enough to treat me as one of h...

BACKGROUND Bleeding on probing (BOP) is an indicator of tissue inflammatory response to bacterial pathogens. Due to anatomical limitations, the entity and physical state of microbial aggregations located under the gingival margin and their relations to BOP have been hardly investigated till now. The recent introduction of the endoscopy has allowed clinicians to observe the subgingival environme...

We have isolated and characterized the light-driven proton pump Bop I from the ultrathin square archaeon Haloquadratum walsbyi, the most abundant component of the dense microbial community inhabiting hypersaline environments. The disruption of cells by hypo-osmotic shock yielded Bop I retinal protein highly enriched membranes, which contain one main 27 kDa protein band together with a high cont...

of the Correlation Matrix Memory (CMM), which is useful to work with binary memories. A novel Boolean Orthonormalization Process (BOP) is presented to convert a non-orthonormal Boolean basis, i.e., a set of non-orthonormal binary vectors (in a Boolean sense) to an orthonormal Boolean basis, i.e., a set of orthonormal binary vectors (in a Boolean sense). This work shows that it is possible to im...

BACKGROUND Positive patch tests to balsam of Peru (BOP) or fragrance mix (FM) suggest the possibility of systemic contact dermatitis from balsam-related foods and spices. OBJECTIVE This was a retrospective study to determine whether avoidance of balsam-related foods results in an improvement of dermatitis in these patients. METHODS A review of the records of all patients seen from July 1 to...

In this article, I examine HP’s e-Inclusion program and its implementation in India to show how the high-tech industry’s efforts to alleviate poverty proatably are guided by C. K. Prahalad’s ideas about the Bottom of the Pyramid (BoP), and are framed as digital corporate citizenship activities. While the BoP highlights the importance of new markets for high-tech companies, the discourse of digi...

Because epidermal growth factor (EGF) is rapidly bound and internalized into rat pancreas, stimulates uptake of tritiated thymidine, and increases pancreatic weight, a cocarcinogenic effect on pancreatic cancer seemed likely. Pancreatic adenocarcinomas were induced in 70 female Syrian hamsters by 19 weekly s.c. injections of N-nitrosobis(2-oxopropyl)amine (BOP) (10 mg/kg). From Wk 5 through Wk ...

In recent years, a considerable amount of research has emerged on business models specifically adapted to the circumstances of the poor population in developing and threshold countries. The concept of “Base of the Pyramid” (BoP) – initiated especially by Prahalad and Hart’s (2002) seminal work – has stirred much attention in both business and academia. It refers to the bottom-tier of the world ...