background: adipose-derived stem cells (adsc) could be an appealing alternative to bone marrow stem cells (bmsc) for engineering cell-based osteoinductive grafts. meanwhile, prior studies have demonstrated that melatonin can stimulate osteogenic differentiation. therefore, we assayed and compared the melatonin effect on osteogenic differentiation of bmsc with that of adsc. methods: mesenchymal ...

bone marrow mesenchymal stem cells can differentiate into neurons and astrocytes after transplantation in the spinal cord injury of rats. although bone marrow mesenchymal stem cells are known to protect against spinal cord injury through anti-apoptotic effects, but generation of neural stem cells with large number and safety protocols unclear. in the present study, described the differentiation...

low-intensity laser therapy (lilt) is defined to supply direct biostimulative light energy to the cells. while several studies have demonstrated that lilt has stimulating effects on bone cells and can accelerate the repair process of the bone, others reported delayed fracture healing or no effects after lilt. the aim of this article was to review the studies evaluating the biomodulation effects...

helicobacter pylori was the main cause of gastric cancer (gc) in all over the world that results in intestinal- and diffuse-type carcinoma. infection by this bacterium remains chronic for a long time. in vitro studies have highlighted the role of stem cells in gc. h. pylori infection results in tissue injury and the adult/tissue stem cells subsequently start to replace the dead cells. the genet...

this investigation aimed to examine the protective function of vitamin e on rat bone marrow mesenchymal stem cells (mscs) treated with cadmium chloride. rat bone marrow mscs were extracted using flashing-out and cultured in dmem containing 10% fbs and 100 u/ml pen/strep. at the end of the third passage, cells were divided into 4 groups including control, cadmium chloride, cadmium chloride + vit...

the wharton’s jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (mscs) which can be therapeutically applied in degenerative diseases. in this study, we investigated the immunomodulatory effect of umbilical cord derived- mesenchymal stem  cells (uc-mscs) and  bone  marrow-derived-mesenchymal stem  cells (bm-mscs) on differentiation, maturation, and endocytosis of m...

Background: This article reviews experimental and clinical studies in which neural injuries repaired with bone marrow stromal cells. History: Bone marrow contains two kinds of stem cells: hematopoietic and nonhematopoietic (stromal) stem cell. In vitro studies indicate that bone marrow stromal cells have the capacity of differentiation into other cells (such as neural cell) under treatment wit...

background infertility is a serious social problem in advanced nations, with male factor in half of all cases of infertility. this study was conducted to determine the regenerative effect of bone marrow-derived stem cells in spermatogenesis of infertile hamster. methods twelve adult male hamsters were equally divided into azoospermic and control groups. busulfan was intraperitoneally used for i...

Introduction: Hematopoiesis is an on going process mammalian marrow system. A few cells from the nucleated cells of bone marrow are hematopoietic cells which include primary stem cells, precursor cells and progenitor cells. Primary stem cells and progenitor cells are able to produce colonies in culture medium (CFU-C) and irradiated mouse spleen (CFU-S). A hematopoietic cell is alive and act...