نتایج جستجو برای: bone marrow necrosis
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UNLABELLED INTRODUCTION Bone marrow necrosis is a clinicopathological condition diagnosed most often at postmortem examination, but it is also seen during the course of malignancy and is not always associated with a poor prognosis. The morphological features of bone marrow necrosis are disruption of the normal marrow architecture and necrosis of myeloid tissue and medullary stroma. Non-malig...
cml in breif cml is characterized by the proliferation of large numbers of immature wbc in the blood and bone marrow. in most of the patients , it is a clonal disorder in which all cell lines, express the philadelphia chromosome)q/22 translocation(it accounts for 20 of all leukemias and most cases occur over 25 yrs of age. the disease usually begins insidiously,but symptoms referable to anemia ...
Bone marrow necrosis (BMN) is defined as necrosis of the myeloid tissues and stroma without involvement of the cortical bone. We report a case of 66-year-old male with AML-M4 (FAB classification) who was given induction chemotherapy with cytarabine and daunorubicin. Filgrastim at 480 micrograms was administered on days 15-19 to shorten the duration of neutropenia. Consequently patient developed...
BACKGROUND Bone marrow necrosis is a relatively rare entity which has been associated with a poor prognosis. It is most commonly found in patients with neoplastic disorders and severe infections. METHODS The study comprised examination of 5043 bone marrow biopsy specimens performed at the National Cancer Institute, Cairo University, over 7 years period (March 2004-March 2011). It included 5 y...
RATIONALE Pegaspargase has been used in the treatment of acute lymphoblastic leukemia with promising results. However, it has also been associated with several potentially serious complications, including thrombosis. Pegaspargase-induced cerebral venous thrombosis and bone marrow necrosis are very rare. PATIENT CONCERNS A 50-year-old female developed headache, weakness of the right lower extr...
The bone marrow is one of the largest organs in the human body (Lund, 2000). It is the major hematopoietic organ and is important as both a primary and secondary lymphoid organ. Since it is a potential target organ of various disorders, evaluation of blood and bone marrow is an important component of any overall assessment studies. Bone marrow evaluation studies provide information about bone m...
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