bone mass loss is one of the commonest menopause symptoms, resulting from cessation of estrogen production. compounds which have estrogen – like biological activity similar to “isoflavones” present in plants especially soy, may reduce bone loss in postmenopausal women, because as they are similar in structure to estrogens. this study, therefore, was undertaken to assess the effect of soy protei...

bone marrow mesenchymal stem cells can differentiate into neurons and astrocytes after transplantation in the spinal cord injury of rats. although bone marrow mesenchymal stem cells are known to protect against spinal cord injury through anti-apoptotic effects, but generation of neural stem cells with large number and safety protocols unclear. in the present study, described the differentiation...

Changes in osteoarthritis joint appear in the articular cartilage, synovium and in subchondral bone. It is necessary to find, apart from markers of cartilage destruction, a sensitive and specific biochemical marker which would reflect the metabolism as well as degradation of subchondral bone. Bone sialoprotein is mostly synthesized in osseous tissue found directly under the surface of joint car...

To the Editor: A recent position paper (1 ) proposed standardization of the nomenclature of bone markers as outlined in Table 1. This position paper has been reviewed and endorsed by the members of the Committee of Scientific Advisors of the International Osteoporosis Foundation. We believe that standardizing the nomenclature of bone markers would be useful to avoid confusion in the literature,...

Metabolism of the bone healing process can be monitored by Bone formation marker, such as alkaline phosphate (ALP). Simvastatin is known to increase marker in repair phase, but its effects on ALP level have not been yet. This study aimed determine effect oral simvastatin administration expression femur fracture a rat model fracture. The research method was experimental post-test only using 18 R...

Methods Bone mineral density (BMD) of the lumbar spine and bilateral proximal femurs (dual energy x-ray absorptiometry) and bone metabolism markers {bone formation marker: serum bone alkaline phosphatase (BAP); bone resorption marker: serum tartrate-resistant acid phosphatase serum band 5 (TRAP5b)} were measured in 55 consecutive AIS subjects aged 10 to 18 years-old (mean: 15.6+/-1.7). BMD, bod...

PURPOSE The ZOTECT study assesses the effect of zoledronic acid (ZOL) on bone-marker levels and potential correlations with disease outcomes in bisphosphonate-naive patients. METHODS This prospective, single-arm, open-label study in bisphosphonate-naive (≥6 months) patients with bone metastases from prostate cancer (PC; n=301) or breast cancer (BC; n=99) enrolled at 98 German sites (May 2006 ...