Introduction: Total body irradiation (TBI) is a form of external beam radiotherapy which is used in conjunction with chemotherapy with the purpose of immunosuppression. Since the target in TBI is the whole body so a uniform dose distribution throughout the entire body during TBI is necessary. As recommended by AAPM dose variation must be within ±10% of prescription dose. A revi...

We examined effects of local and whole body irradiation before tooth extraction on appearance and differentiation of osteoclasts in the alveolar bone of rat maxillary first molars. Wistar rats weighting 100 g were divided into three groups: non-irradiation group, local irradiation group, and whole body irradiation group. In the local irradiation group, a field made with lead blocks was placed o...

PURPOSE Ablative bone marrow irradiation is an integral part of hematopoietic stem cell transplantation. These treatment regimens are based on classically held models of radiation dose and the bone marrow response. Flt-3 ligand (FL) has been suggested as a marker of hematopoiesis and bone marrow status but the kinetics of its response to bone marrow irradiation has yet to be fully characterized...

The mechanism of pain relief by low–power laser (Ga–Al–As diode laser, 16.2 mW) irradiation was studied using the patch–clamp technique in cultured mouse dorsal root ganglion neurons as sociated with C–fiber. Bradykinin (BK) and laser stimulation was limited to the process or the cell body using a specially developed separator. The action potentials of the cell body after BK application to the ...

The effect of ionizing irradiation on testes and the protective effects of melatonin were investigated by immunohistochemical and electron microscopic methods. Eighty-two adult male Wistar rats were divided into 10 groups. The rats in the irradiated groups were exposed to a sublethal irradiation dose of 8 Gy, either to the total body or abdominopelvic region using a 60Co source at a focus of 80...

Background: Total Body Irradiation (TBI) is different from standard radiotherapy in many aspects, so it is not easy to predict the delivered dose to the patient under TBI treatment. Diode dosimetry procedures for surface dose reading can help to define variations of the actually delivered dose from the prescribed one. The aim of this study was to describe the measurements made to calib...