UNLABELLED Body fluid composition is maintained in a normal physiologic range by regulatory mechanisms that control sodium and water metabolism. A detailed knowledge of the homeostatic mechanisms will help in understanding the pathogenesis and management of disorders of sodium and water balance. OBJECTIVES After completing this article, readers should be able to: 1. Understand the distributio...

1 Department of Occupational Medicine, Chi Mei Medical Center, Tainan 710, Taiwan 2Department of Paediatrics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong 3Medical Proteomics Unit, Office for Research and Development, Faculty of Medicine Siriraj Hospital, and Center for Research in Complex Systems Sci...