objective(s): haemostasis prevents blood loss following vascular injury. it depends on the unique concert of events involving platelets and specific blood proteins, known as coagulation factors. the clotting system requires precise regulation and coordinated reactions to maintain the integrity of the vasculature. clotting insufficiency mostly occurs due to genetically inherited coagulation fact...

background recombinant activated factor vii (rfviia; novoseven® rt, novo nordisk, bagsvaerd, denmark) is a synthetic pro-coagulation factor derived from hamster kidney cells. objectives the purpose of this study was to evaluate the prescribing patterns of recombinant factor viia (rfviia) at a single, tertiary care pediatric hospital by indication of usage and dose administered. materials and me...

multiple sclerosis (ms) is a neuroinflammatory autoimmune disease which mediated by various molecular and cellular immune components however recent reports have shown that coagulation factors that traditionally separate from the immune system might also be involved in ms development and progression.studies on experimental autoimmune encephalomyelitis (eae) and human ms patients reports alterati...

The blood coagulation system of 66 consecutive patients undergoing consecutive liver transplantations was monitored by thrombelastograph and analytic coagulation profile. A poor preoperative coagulation state, decrease in levels of coagulation factors, progressive fibrinolysis, and whole blood clot lysis were observed during the preanhepatic and anhepatic stages of surgery. A further general de...

Objective(s): Haemostasis prevents blood loss following vascular injury. It depends on the unique concert of events involving platelets and specific blood proteins, known as coagulation factors. The clotting system requires precise regulation and coordinated reactions to maintain the integrity of the vasculature. Clotting insufficiency mostly occurs due to genetically inherited coagulation fact...

Multiple sclerosis (MS) is a neuroinflammatory autoimmune disease which mediated by various molecular and cellular immune components However Recent reports have shown that coagulation factors that traditionally separate from the immune system might also be involved in MS development and progression.studies on experimental autoimmune encephalomyelitis (EAE) and human MS patients reports alterati...

HERBERT S. SLSE, JACQUES GAUTHIEB, ROBERT BECKER AND JOHN Boz. c n H EMORRHAGE has been an important and ominous sign in victims of irradiation effects. Although its occurrence coincided with a period of intense thrombocytopenia, Allen and Jacobson1 in experimental observations in dogs observed a circulating heparin-like anticoagulant, and Allen2 concluded that it played an important role in th...

KB We usually use prestorage leukoreduced red blood cells to treat symptomatic anemia, and leukoreduced apheresis platelets or whole blood–derived platelets to treat thrombocytopenia. Plasma components are used less commonly, and their use generally is restricted to the treatment of bleeding associated with coagulation factor deficiencies—either isolated coagulation factors or multiple coagulat...

(A review of the blood coagulation system of fish). Hemostasis is a function of paramount importance when an animal is responding to an injury or has a blood coagulation disorder. It is important to stop the bleeding after a vascular injury, in order to prevent blood loss, so the body needs an effective coagulation mechanism. In fish, despite the fact that there are many studies about the intri...