breast cancer is the most common cancer in women worldwide. breast cancer in one third of all patients will go on to metastasis, which is the main cause of mortality in cancer cases. tumor cells detach from primary tumor and enter into the circulation as circulating tumor cells (ctcs) which can form metastatic lesions. in this study, the expression of ck-19 gene in blood samples of metastatic b...

background: animal suitable models are very useful tools in the studies of complicated diseases. in this way we can study the heterogeneity of human genome and also we can minimize the effect of environmental factors in the incidence of cancers. in this study the expression of vwf and pcna in tumors was determined by immunohistochemistry and also we measured three cancer markers and two blood f...

Background:Leukemia is cancer of blood and bone marrow cells. In general, there are four types of leukemia: chronic myelogenous leukemia (CML), acute myeloid leukemia (AML), B-cell chronic lymphocytic leukemia (CLL) and acute lymphoblastic leukemia (ALL).  Fractal geometry can be introduced as one of the effective ways to detect this type of cancer. In this study, with introduc...

Background: To explore a possible rela!onship among blood groups and the prognosis of breast cancer, this case- control study was carried out in Arak city, Arak province, Iran. Materials and Methods: One hundred and thirty four pa!ents with breast cancer were inves!gated. ABO blood groups were obtained from medical records. Mul!variate analyses were performed, including size of tumor, axilla...

background while colorectal cancer (crc) is one of the most preventable causes of cancer mortality, it is one of the leading causes of cancer death in canada where crc screening uptake is suboptimal. given the increased rate of mortality and morbidity among mental health patients, their condition could be a potential barrier to crc screening due to greater difficulties in adhering to behaviours...

this article reviews the recently published data on the diagnosis of cancer with proteomics, including the major proteomics technologies and promising strategies for biomarker discovery and development.  most of the tumor markers are proteins that either numerically increase in response to the alteration of cancer conditions or are produced by cancer cells. however, they are natural compounds o...

background: cancer is the third cause of death in iran and its incidence is rising alarmingly. however, a study reported that kohgilooyeh and boyerahmad (a small province in iran) seems to have substantially lower incidence rate of cancer compared to the other parts of the country. this study is conducted to investigate the epidemiological features of cancer regarding three key factors (sex, ag...

breast carcinoma is the major cause of cancer-related death in women. the incidence of this carcinoma is rising and there are many attempts to decrease this problem. the aim of this study was detection of full-length cytokeratin 19 (ck19) mrna, in peripheral blood and tissue of breast cancer patients in early stage of cancer. in this study, rt-pcr (reverse transcriptase-polymerase chain reactio...