Le lichen blaschko-linéaire constitue une forme rare (0,5 %) du lichen plan dont l'âge moyen de survenue est de 50ans. Il est plus fréquent chez l'homme. Sa disposition linéaire en dehors du phénomène de Koebner serait due au mosaicisme génétique responsable de la présence d'un clone kératinocytaire capable de réagir sous l'effet de facteurs immunogènes, exogènes ou infectieux. Le traitement re...

Linear psoriasis is an unusual clinical variation of psoriasis that manifests segmentally along the lines of Blaschko. A major differential diagnosis is inflammatory linear verrucous epidermal nevus (ILVEN). The treatment of linear psoriasis is often challenging, with inadequate response to biological agents reported in the literature. We report a case of a 25-year-old African-American female w...

Linear acantholytic dermatoses are a spectrum of cutaneous disorders that form a subset of linear dermatoses with distinct clinical features and histopathologically show acantholysis. The lesions may be zosteriform or follow the lines of Blaschko. This report describes a four-year-old boy who, on a follow up of two years, exhibited a relapsing acantholytic dermatosis along the lines of Blaschko...

Atypical and unusual locations of psoriasis are very frequent. However, localized linear psoriasis is rare, with few cases described in the literature. It is characterized by a linear distribution of psoriasis lesions along Blaschko lines. We report the case of a three years old child, who presented unilateral erythematous scaly plaques arranged along Blaschko lines in the left hemithorax, with...

Lichen planus is an uncommon disease in children, and only 2 to 3% of affected patients are under twenty years of age. This dermatosis may appear in several clinical forms, which vary according to the morphology and distribution of lesions. In less than 0.2% of all lichen planus cases, the lesions are distributed along the lines of Blaschko, and is a variant called linear lichen planus. This is...

A mosaic is an organism composed of two or more genetically distinct cell populations derived from a genetically homogeneous zygote. Cutaneous mosaicisms are the clinical expressions of these disorders. The main event which allows the existence of mosaicism is a genetic mutation, either structural or functional. Cutaneous mosaicisms usually manifest by specific patterns on the skin and the arch...

BLAISE: blaschkolinear acquired inflammatory skin eruption INTRODUCTION Blaschkolinear acquired inflammatory skin eruption (BLAISE) encompasses a variety of skin conditions in children and adults that show striking distribution along the lines of Blaschko and are characterized histopathologically by an inflammatory infiltrate. The most common presentations of BLAISE are blaschkitis, which affec...