This study reveals the presence of different carbapenemase genes (blaKPC, blaNDM, blaGES, and blaOXA48-like genes) detected directly from water samples and clonal dispersion (by pulsed-field gel electrophoresis [PFGE] and multilocus sequence typing [MLST]) of KPC-2-producing Enterobacteriaceae in two important urban aquatic matrixes from Rio de Janeiro, Brazil, highlighting the role of aquatic ...

Serratia marcescens is a Gram-negative rod intrinsically resistant to polymyxins and usually associated with wound, respiratory and urinary tract infections. The whole genome of the first GES-5-producing S. marcescens isolated from a Brazilian patient was sequenced using Ion Torrent PGM System. Besides blaGES-5, we were able to identify genes encoding for other β-lactamases, for aminoglycoside ...

Ab stract Use-wear and tech no log i cal stud ies sug gest that Natufian flint as sem blages share sev eral char ac ter is tics with Mesolithic as sem blages of Eu rope, as both re gions show an ex ten sive pro duc tion of mi cro-lithic tools mostly de voted to an i mal pro cure ment and ex ploi ta tion. In the Lev ant, this as so ci a tion seems to be rooted in pre vi ous cul tural tra di tion...

Acinetobacter baumannii (A. baumannii) is a highly problematic pathogen with an enormous capacity to acquire or upregulate antibiotic drug resistance determinants. The genomic epidemiology and resistome structure of 46 A. clinical isolates were studied using whole-genome sequencing. chosen based on reduced susceptibility at least three classes antimicrobial compounds initially identified MALDI-...

The ear li est oc cur rences of per sonal or na ments in West ern Eur asia are known from as sem blages that are placed at the Mid dle to Up per Paleolithic Tran si tion (Chatelperronian, Uluzzian, Blattspitzengruppen, Bachokirian). How ever, the pau city of sites dat ing to this pe riod which have pro duced such or na ments, the of ten doubt ful con tex tual as so ci a tion of the finds, and t...

Plasmid-located extended-spectrum-lactamase (ESBL) genes are mostly found in Enterobacteriaceae (6). A new class A ESBL was identified in Klebsiella pneumoniae. It was named GES-1, and it corresponds to the ceftazidime-hydrolyzing enzyme (8). GES-type ESBLs have emerged in a variety of countries, and there are 18 known variants (http://www.lahey.org/Studies/). In the present study, we investiga...

In this brief communication we describe the occurrence of a KPC-producing Serratia marcescens isolate in a home-care patient from Recife, Brazil. The blaKPC, blaSPM, blaIMP, blaVIM, blaOXA, blaCTX-M, blaSHV, blaTEM and blaGES genes were investigated by Polymerase Chain Reaction (PCR) and DNA sequencing. The isolate was positive for blaKPC-2 and blaTEM-1 and was resistant to aztreonam, cefepime,...

Among the 2,105 Enterobacteriaceae tested in a survey done in Portugal, 165 were nonsusceptible to carbapenems, from which 35 (26 Klebsiella pneumoniae, 3 Escherichia coli, 2 Enterobacter aerogenes, and 3 Enterobacter cloacae isolates and 1 Klebsiella oxytoca isolate) were confirmed to be carbapenemase producers by the presence of 30 Tn4401d-blaKPC-3, 4 intI3-blaGES-5, and one intI1-blaVIM-2 ge...

Antimicrobial-resistant bacteria and resistance determinants are of great concern to human veterinary medicine worldwide. Extended-spectrum ?-lactamase (ESBL)-producing resistant broad-spectrum cephalosporins. ESBL-producing isolates, including those carrying blaCTX, blaPER, blaVEB, blaGES, have been reported from rivers in several countries.1 In a study performed 2018, using next-generation se...