BACKGROUND Some genetic and phenotypic variables are associated among distinct microbial populations. OBJECTIVES The associations between multi-drug resistance (MDR) phenotypes, prevalence of antibiotic resistance integrons (ARIs), bla SHV, bla TEM and bla CTX-M gene carriage and genetic fingerprints of random amplified polymorphic DNA (RAPD), confirmed by pulsed field gel electrophoresis (PF...

OBJECTIVES Previously 14 conjugative plasmids from multi-drug resistant (MDR) Escherichia coli from healthy humans and food-producing animals in Switzerland were sequenced. The aim of this study was to extend the genetic characterization of these plasmids with a focus on bla ESBL genes including bla CTX-M-1 and bla TEM, class 1 integrons and toxin-antitoxin (TA) systems contained therein. MET...

BACKGROUND Extended-spectrum β-lactamase (ESBL)-encoding genes are frequently mapped to plasmids, yet few of these structures have been characterized at the molecular level, to date. METHODS Eighty-seven ESBL-producing Escherichia coli were isolated from fecal samples of food-producing animals and healthy humans in Switzerland from 2009 to 2011. Plasmid DNA of all isolates was purified. Broth...

conclusions: our findings suggest the possible co-carriage of some blashv genes and aris on the same plasmids harboring the mdr genes. possible role of integrons in dissemination of esbl-encoding blashv genes among esbl-producing k. pneumoniae nosocomial isolates may be inferred. background: some genetic and phenotypic variables are associated among distinct microbial populations. objectives: t...

There is growing evidence that Enterobacteriaceae harboring clinically relevant bla genes, especially genes encoding the CTX-M family of extended-spectrum -lactamases (ESBLs), have spread into the environment (1). The purposes of this study were (i) to investigate the occurrence of expanded-spectrum-cephalosporinresistant Enterobacteriaceae in intestines of fish captured from Lake Zürich and La...