thirty six wistar albino rats with implant induced endometriosis were randomly divided into six groups of six animals each. the rats in the first group received nothing and were euthanized at day 21. in the second group, rats received nothing and were euthanized at day 36. the third group received atorvastatin (atv; 5 mg kg-1 per day, orally) until 21 days from induction of endometriosis, and t...

BACKGROUND One of the known complications of diabetes mellitus is vascular dysfunction. Inability of the coronary vascular response to cardiac hyperactivity might cause a higher incidence of ischemic heart disease in diabetic subjects. It has been indicated that regular exercise training and antioxidants could prevent diabetic cardiovascular problems enhanced by vascular damage. OBJECTIVES Th...

conclusions in conclusion, taking gse for eight weeks had beneficial effects on the plasma gsh, mda levels, and markers of insulin metabolism of female volleyball players. results supplementation with gse resulted in a significant rise in the plasma glutathione (gsh) level (+265.5 ± 344.2 vs. +2.2 ± 378.2 µmol/l, p = 0.02), as well as a significant decrease in the malondialdehyde (mda) level (-...

Polyphenol-rich grape seed extract (0.1 w/w%) was incorporated in liposomes (1 w/w% soy lecithin) by high pressure homogenization (22,500 psi) and coated with chitosan (0.1 w/w%). Primary liposomes and chitosan-coated secondary liposomes containing grape seed extract showed good physical stability during 98 days of storage. Most of the polyphenols were incorporated in the shell of the liposomes...

The purpose of present study was to investigate the effect of water and ethanol extracts of red grape seeds on inhibition of pancreatic -amylase and lipase in vitro. Total proanthocyanidins were determined in grape seed extracts (GSEs). Different concentrations (400, 800, 1300 and 1800 ppm) of each GSE were employed to evaluate their potentials on pancreatic -amylase and lipase after pre-incuba...

conclusions the data indicated that co-administration of grape seed extract and exercise training had more significant effects than exercise training or grape seed extract alone; this may constitute a convenient and inexpensive therapeutic approach to diabetic vascular complications. results the endothelium dependent vasorelaxation to acetylcholine was reduced significantly in diabetic animals;...

In one study, 287 patients diagnosed with asymptomatic carotid plaques or abnormal plaque free carotid intima-media thickness (CIMT) were randomly assigned to a GSE group (n = 146) or control group (n = 141). As anticipated, after treatment, GSE resulted in significant reduction in MMCIMT progression, while MMCIMT and plaque score were stable and even increased with the control group. The numbe...

Grape-seed proanthocyanidins’ role as stimulators of active GLP-1 in rats suggests that they could be effective as satiating agents. Wistar rats were used to study the effects of proanthocyanidins on food intake with different doses, administration times and proanthocyanidin extract compositions. A dose of 423 mg of phenolics per kg body weight (BW) of grape-seed proanthocyanidin extract (GSPE)...

The crude seed extract of neem, black pepper, mahogani, and garlic bulb with three doses were evaluated against legume pod borer in the country bean field in two seasons kharif 2006 and rabi 2006-2007. The neem seed extract applied @150 and 100 g/l and mahogani seed extract @ 100 g/l of water 7 days intervals on the country bean showed better performance in the reduction of flower and pod damag...